CEREBRAL BLOOD-FLOW AND METABOLIC-RATE DURING SEIZURES - RELATIONSHIP TO EPILEPTIC BRAIN-DAMAGE
CEREBRAL BLOOD-FLOW AND METABOLIC-RATE DURING SEIZURES - RELATIONSHIP TO EPILEPTIC BRAIN-DAMAGE
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DOI：
10.1111/j.1749-6632.1986.tb51254.x
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发表时间：
1986-03-14
影响因子：
5.2
通讯作者：
INGVAR, M
中科院分区：
文献类型：
--
作者：
INGVAR, M
结论长时间的神经元过度活动伴随着葡萄糖代谢率的增加是神经元损伤发展的先决条件。然而，SNPR的坏死表明其他因素决定了神经元对过度兴奋的脆弱性，例如，作用于神经元的激动剂的类型。
Conclusionprolonged neuronal hyperactivity with a concomitant increase in the metabolic rate for glucose is a prerequisite for the development of neuronal damage. However, the necrosis of the SNPR demonstrates that other factors determine the vulnerability of neurons to hyperexcitation, eg, the type of agonist acting on the neuron.