Comparative Study of Magnetic Resonance Imaging and Image-Based Computational Fluid Dynamics for Quantification of Pulsatile Flow in a Carotid Bifurcation Phantom
Comparative Study of Magnetic Resonance Imaging and Image-Based Computational Fluid Dynamics for Quantification of Pulsatile Flow in a Carotid Bifurcation Phantom
复制标题
DOI：
10.1114/1.1590664
复制
发表时间：
2003-09
影响因子：
3.8
通讯作者：
Shunzhi Zhao;P. Papathanasopoulou;Quan Long;I. Marshall;Xiao Yun Xu
中科院分区：
文献类型：
--
作者：
Shunzhi Zhao;P. Papathanasopoulou;Quan Long;I. Marshall;Xiao Yun Xu
采用磁共振成像(MRI)和计算流体动力学(CFD)相结合的方法，对颈动脉分叉模型中的脉动流进行了模拟研究。这项研究的目的是量化MRI测量和基于MRI的CFD模拟之间的流动模式的差异，并进一步探索活体应用的潜力。计算模型是根据高分辨率磁共振(MR)扫描重建的。由相衬磁共振测量得到的速度被用作CFD计算的边界条件。将CFD结果与MRI测量结果进行了详细的比较。正常血流(颈总动脉)和扰动区(颈动脉窦)的主要血流速度分量有很好的一致性。平面内速度矢量的比较显示一致性较差，并且表明所获得的MR测量结果不足以描述预期的二次流流型。可以认为，MRI/CFD联合应用有望提供更可靠的全三维速度场信息。©2003生物医学工程学会.PAC2003：8761Lh，8719Uv，8385pt，8710+e
A combined magnetic resonance imaging (MRI) and computational fluid dynamics (CFD) modeling study was carried out for pulsatile flow in a carotid bifurcation phantom. The aim of the study was to quantify differences in flow patterns between MRI measurement and MRI-based CFD simulations and to further explore the potential forin vivoapplications. The computational model was reconstructed from high resolution magnetic resonance (MR) scans. Velocities derived from phase-contrast MR measurements were used as boundary conditions for the CFD calculation. Detailed comparisons of velocity patterns were made between the CFD results and MRI measurements. Good agreement was achieved for the main velocity component in both well-behaved flow (in the common carotid) and disturbed region (in the carotid sinus). Comparison of in-plane velocity vectors showed less satisfactory consistency and revealed that the MR measurements obtained were inadequate to depict the secondary flow pattern as expected. It can be concluded that the combined MRI/CFD is expected to provide more reliable information about the full three-dimensional velocity field. ©2003 Biomedical Engineering Society.PAC2003: 8761Lh, 8719Uv, 8385Pt, 8710+e