Influence of surfactant assembly on the formation of calcium phosphate materials - A model for dental enamel formation
Influence of surfactant assembly on the formation of calcium phosphate materials - A model for dental enamel formation
复制标题
DOI：
10.1039/b503312h
复制
发表时间：
2005-01-01
影响因子：
--
通讯作者：
Margolis, HC
中科院分区：
文献类型：
--
作者：
Fowler, CE;Li, M;Margolis, HC
以表面活性剂琥珀酸双（2-乙基己基）酯磺酸钠（AOT）、水和油为原料合成了新型磷酸钙材料。通过改变溶液组分的相对浓度获得了一系列的形态。从高粘度反应溶液中制备具有类似牙釉质的结构特征的材料。该材料由长750 nm（~ 1）μ m、宽250-350 nm的共排列细丝束组成。每束包含10-20根细丝，被鉴定为羟基磷灰石晶体。束的电子衍射导致弧形图案指示伸长的对齐晶体，并且类似于已知的牙釉质。像这样的系统可以用作模型，以深入了解牙釉质生物矿化的机制。重要的是，我们提供了新的证据支持的假设，在自然界中的层次结构的有机组装和晶体生长之间的合作相互作用的结果。无定形磷酸钙纳米颗粒，空心球，球形磷酸八钙聚集体的板和细长板的磷酸氢钙二水合物也得到了在不同的条件下，改变AOT组装和溶液粘度。后者的这些发现进一步说明了有机组装对磷酸钙材料形成的重要影响。
Novel calcium phosphate materials were synthesized from solutions containing the surfactant bis(2-ethylhexyl)sulfosuccinate sodium salt (AOT), water and oil. A range of morphologies was obtained by varying the relative concentrations of the solution components. A material with structural features resembling tooth enamel was produced from a highly viscous reaction solution. This material consisted of bundles of co-aligned filaments, 750 nm(-1) mu m in length and 250-350 nm wide. Each bundle contained 10-20 filaments, identified as hydroxyapatite crystals. Electron diffraction of the bundles resulted in an arc pattern indicative of elongated aligned crystals, and similar to that known for dental enamel. Systems such as this may be used as models to gain insight into the mechanisms involved in the biomineralization of tooth enamel. Importantly, we have provided new evidence in support of the hypothesis that hierarchical structures in nature result from cooperative interactions between organic assembly and crystal growth. Amorphous calcium phosphate nanoparticles, hollow spheres, spherical octacalcium phosphate aggregates of plates and elongated plates of calcium hydrogen phosphate dihydrate were also obtained under different sets of conditions that altered AOT assembly and solution viscosity. These latter findings illustrate further the significant influence of organic assembly on the formation of calcium phosphate materials.