NEUROPSYCHOLOGICAL OUTCOME AND QUANTITATIVE IMAGE-ANALYSIS OF ACUTE HEMORRHAGE IN TRAUMATIC BRAIN INJURY - PRELIMINARY FINDINGS
NEUROPSYCHOLOGICAL OUTCOME AND QUANTITATIVE IMAGE-ANALYSIS OF ACUTE HEMORRHAGE IN TRAUMATIC BRAIN INJURY - PRELIMINARY FINDINGS
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DOI：
10.3109/02699059409151001
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发表时间：
1994-08-01
期刊：
影响因子：
1.9
通讯作者：
BLATTER, DD
中科院分区：
文献类型：
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作者：
KURTH, SM;BIGLER, ED;BLATTER, DD
本研究旨在探讨脑外伤(TBI)患者急性出血量、损伤体积和损伤部位对神经心理结局的影响。出血灶体积与损伤严重程度相关。然而，点状出血的数量与任何临床结果指标都没有可靠的相关性。同样，尽管使用了详细的形态计量学方法来量化体积，但急性病变的大小与神经心理后遗症没有明显的关系。此外，脑象限定位方法并不能增强结果预测。这些结果在急性损伤分析的背景下进行了讨论，并与慢性脑损伤引起的神经病理改变与神经心理结果进行了对比。
The effect on neuropsychological outcome of the number of acute haemorrhages, lesion volume, and lesion location in traumatic brain injury (TBI) was evaluated. Haemorrhagic lesion volume was associated with severity of injury. However, the number of petechial haemorrhages was not reliably associated with any of the clinical outcome measures. Likewise, despite the use of detailed morphometric methods to quantify volume, the acute lesion size did not significantly relate to neuropsychological sequelae. Furthermore, brain quadrant localization methods did not enhance outcome prediction. These results are discussed in the context of acute lesion analysis contrasted with chronic TBI-induced neuropathological changes associated with neuropsychological outcome.