Masked Hypertension Defined by Home Blood Pressure Monitoring Is Associated With Impaired Flow-Mediated Vasodilatation in Patients With Cardiovascular Risk Factors
Masked Hypertension Defined by Home Blood Pressure Monitoring Is Associated With Impaired Flow-Mediated Vasodilatation in Patients With Cardiovascular Risk Factors
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DOI：
10.1111/jch.12155
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发表时间：
2013-09-01
影响因子：
2.8
通讯作者：
Kario, Kazuomi
中科院分区：
文献类型：
--
作者：
Kabutoya, Tomoyuki;Hoshide, Satoshi;Kario, Kazuomi
家庭血压（BP）、由家庭血压定义的隐性高血压和综合血流介导的血管舒张（FMD）反应之间的关系尚不清楚。作者招募了257名患者（平均年龄63.5岁; 51%为男性），他们至少有一个心血管危险因素。肱动脉的FMD用半自动边缘检测算法测量。积分FMD响应计算为回缩后120秒内的扩张曲线下面积（FMD-AUC 120），FMD幅度计算为峰直径（FMD）的百分比变化。隐匿性高血压的定义是办公室血压
The relationships between home blood pressure (BP), masked hypertension defined by home BP, and integrated flow-mediated vasodilation (FMD) response remain unclear. The authors enrolled 257 patients (mean age, 63.5years; 51% men) who had at least one cardiovascular risk factor. FMD of the brachial artery was measured with a semiautomatic edge-detection algorithm. The integrated FMD response was calculated as the area under the dilation curve during 120seconds after deflation (FMD-AUC120) and the FMD magnitude as the percentage change in peak diameter (FMD). Masked hypertension was defined by office BP