Recurrence of endometriosis: risk factors, mechanisms and biomarkers
Recurrence of endometriosis: risk factors, mechanisms and biomarkers
复制标题
DOI：
10.2217/whe.15.56
复制
发表时间：
2015-09-01
期刊：
影响因子：
2.4
通讯作者：
Bozdag, Gurkan
中科院分区：
文献类型：
--
作者：
Bozdag, Gurkan
在严重痛经/慢性盆腔疼痛的女性中，子宫内膜异位症的发生率高达40-60%，而生育能力低下的患者的风险高达20-30%。在有症状的患者中，虽然药物治疗是子宫内膜异位症患者的首选，但对无反应或子宫内膜异位症患者可能需要手术治疗。手术后，疾病和/或症状可能会随着时间的推移而逐渐复发。尽管如此，已经确定了一些降低手术成功率的复发风险因素。这些危险因素可分为与患者疾病相关的和与手术相关的变量。在此，我们将讨论子宫内膜异位症复发的危险因素、复发机制和潜在的生物标志物来预测事件。
While the incidence of endometriosis is up to 40-60% in women with severe dysmenorrhea/chronic pelvic pain, patients with subfertility carries a risk up to 20-30%. In symptomatic patients, although medical therapy is preferred in women with endometriosis, surgery might be needed in nonresponders or patients with an endometrioma. Following the surgery, recurrence of the disease and/or symptoms might be still noticed which will progressively increase as times goes by. Nevertheless, some risk factors have been identified for the risk of recurrence that decreases the success of the procedure. Those risk factors might be classified as patient-disease related and surgery-associated variables. Herein, we will address about the management of endometriosis regarding the risk factors for relapse, mechanisms of recurrence and potential biomarkers to predict the event.