OESOPHAGEAL CANCER AND ALCOHOLIC SPIRITS IN CENTRAL AFRICA
OESOPHAGEAL CANCER AND ALCOHOLIC SPIRITS IN CENTRAL AFRICA
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DOI：
10.1136/gut.10.8.643
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发表时间：
1969-01-01
期刊：
影响因子：
24.5
通讯作者：
MCGLASHAN, ND
中科院分区：
文献类型：
--
作者：
MCGLASHAN, ND
一个大面积的地理病理学调查，在中部非洲的描述和对比是公认的相邻地区之间的食管癌病例显然很多，显然很少。首先将这一分布情况与撒哈拉以南非洲其他已知的高发病率和低发病率地区进行比较，然后与饮用土著类型蒸馏酒的情况进行比较。一个显着的空间相关性的顺序之间的地理格局的疾病和饮用糖基酒精在中部非洲。来自赞比亚东部、肯尼亚中部和特兰斯凯的烈酒样本，尽管使用的器皿明显不同，但都显示出不同程度的锌污染。在所有这些地区的土著烈酒中也有亚硝胺类化合物的报道，说明了对非洲土著饮酒习惯进行地理调查的必要性。由于禁止蒸馏的立法是无效的，应该确定一种简单的方法，从非法酒精中排除致癌化合物，并在乡村一级广泛宣传。
A geographical pathology survey of a large area in central Africa is described and a contrast is recognized between neighbouring areas with apparently many and apparently few cases of oesophageal cancer. This distribution is compared first with other known areas of high and low incidence in sub-Saharan Africa and then with the drinking of indigenous types of distilled spirits. A significant order of spatial correlation is shown between the geographical pattern of the disease and the drinking of sugar-based alcoholic spirit in central Africa. Samples of spirits from eastern Zambia, central Kenya, and the Transkei, although prepared in apparently dissimilar utensils, were all shown to be contaminated in varying degree with zinc. Nitrosamine-like compounds in native spirits were also reported in all these areas.The need for a geographical survey of indigenous drinking habits in Africa is illustrated. Since legislation against distilling is ineffective, a simple means of excluding carcinogenic compounds from illicit spirits should be ascertained and widely promulgated at village level.