Design of a water coupling bolus with improved flow distribution for multi-element superficial hyperthermia applicators.
Design of a water coupling bolus with improved flow distribution for multi-element superficial hyperthermia applicators.
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DOI：
10.3109/02656730903124506
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发表时间：
2009-11
期刊：
影响因子：
--
通讯作者：
Stauffer PR
中科院分区：
文献类型：
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作者：
Arunachalam K;Maccarini PF;Schlorff JL;Birkelund Y;Jacobsen S;Stauffer PR
在浅表热疗中使用的水团将电磁（EM）或声能耦合到目标组织中，并冷却组织表面以最小化治疗期间的热热点和患者不适。在这项研究中，使用三维流体动力学模拟计算的团内的流体压力的参数分析，以确定一个团的设计与改进的流量和表面温度分布的大面积表面热施加器。模拟结果被用于设计和制造一个19×32 cm的原型团与双输入-双输出（DIDO）的流动通道。使用针对循环水温度的阶跃变化记录的团表面温度的顺序热图像来评估整个团的稳态流量和表面温度分布。建模和测量数据表明，从以前的单输入单输出（SISO）到DIDO配置时，团流和表面温度分布有了很大的改善。与SISO水团的1.5°C相比，DIDO水团在稳态下测量的整个团的温度变化小于0.8°C。新的DIDO团配置在通常在浅表热疗中治疗的大面积上保持几乎均匀的流量分布和表面温度的低变化。
A water bolus used in superficial hyperthermia couples the electromagnetic (EM) or acoustic energy into the target tissue and cools the tissue surface to minimize thermal hotspots and patient discomfort during treatment. Parametric analyses of the fluid pressure inside the bolus computed using 3D fluid dynamics simulations are used in this study to determine a bolus design with improved flow and surface temperature distributions for large area superficial heat applicators. The simulation results are used in the design and fabrication of a 19×32 cm prototype bolus with dual input-dual output (DIDO) flow channels. Sequential thermal images of the bolus surface temperature recorded for a step change in the circulating water temperature are used to assess steady state flow and surface temperature distributions across the bolus. Modeling and measurement data indicate substantial improvement in bolus flow and surface temperature distributions when changing from the previous single input-single output (SISO) to DIDO configuration. Temperature variation across the bolus at steady state was measured to be less than 0.8°C for the DIDO bolus compared to 1.5°C for the SISO waterbolus. The new DIDO bolus configuration maintains a nearly uniform flow distribution and low variation in surface temperature over a large area typically treated in superficial hyperthermia.