Haemophilus influenzae type b and Streptococcus pneumoniae as causes of pneumonia among children in Beijing, China
Haemophilus influenzae type b and Streptococcus pneumoniae as causes of pneumonia among children in Beijing, China
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DOI：
10.3201/eid0602.000209
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发表时间：
2000-03-01
影响因子：
11.8
通讯作者：
Yang, YH
中科院分区：
文献类型：
--
作者：
Levine, OS;Liu, G;Yang, YH
为了确定是否流感嗜血杆菌B型（HiB）和肺炎链球菌更容易从肺炎患者的鼻咽部比从对照组患者，我们获得了鼻咽拭子标本从96例胸部X线确诊的肺炎和214例年龄匹配的腹泻或皮炎从北京儿童医院门诊部的对照组患者。肺炎患者更有可能感染Hib和S。即使在数据调整了可能的混杂因素，如日托，家庭中其他儿童的存在，以及最近的抗生素使用后，肺炎患者的死亡率也高于对照组。在中国，肺炎患者的血培养很少呈阳性，这些鼻咽培养的结果为Hib和S的作用提供了支持证据。肺炎是儿童肺炎的原因。
To determine if Haemophilus influenzae type b (Hib) and Streptococcus pneumoniae could be identified more often from the nasopharynx of patients-with pneumonia than from control patients, we obtained nasopharyngeal swab specimens from 96 patients with chest x-ray-confirmed pneumonia and 214 age-matched control patients with diarrhea or dermatitis from the outpatient department at Beijing Children's Hospital. Pneumonia patients were more likely to be colonized with Hib and S. pneumoniae than control patients, even after the data were adjusted for possible confounding factors such as day-care attendance, the presence of other children in the household, and recent antibiotic use. In China, where blood cultures from pneumonia patients are rarely positive, the results of these nasopharyngeal cultures provide supporting evidence for the role of Hib and S. pneumoniae as causes of childhood pneumonia.