Functional interactions of the inferior frontal cortex during the processing of words and word-like stimuli
Functional interactions of the inferior frontal cortex during the processing of words and word-like stimuli
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DOI：
10.1016/s0896-6273(01)00288-4
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发表时间：
2001-05-01
期刊：
影响因子：
16.2
通讯作者：
Horwitz, B
中科院分区：
文献类型：
--
作者：
Bokde, ALW;Tagamets, MA;Horwitz, B
通过确定这些区域与左枕叶和颞叶皮层的功能连接模式，验证了左额下回（LIFG）的腹侧/前部参与语义加工，背侧/后部参与语音加工的假设。根据这一假设，我们发现腹侧LIFG活动与枕叶和颞叶皮层活动之间的功能连接仅限于单词，而背侧LIFG活动与枕叶和颞叶皮层活动之间的功能连接仅限于单词、假单词和字母串，但不包括假字体串。这些结果表明LIFG在其与后脑区的功能联系方面具有任务依赖性功能分级。
The hypothesis that ventral/anterior left inferior frontal gyrus (LIFG) subserves semantic processing and dorsal/posterior LIFG subserves phonological processing was tested by determining the pattern of functional connectivity of these regions with regions in left occipital and temporal cortex during the processing of words and word-like stimuli. In accordance with the hypothesis, we found strong functional connectivity between activity in ventral LIFG and activity in occipital and temporal cortex only for words, and strong functional connectivity between activity in dorsal LIFG and activity in occipital and temporal cortex for words, pseudowords, and letter strings, but not for false font strings. These results demonstrate a task-dependent functional fractionation of the LIFG in terms of its functional links with posterior brain areas.