miRBase: tools for microRNA genomics.

miRBase: tools for microRNA genomics.
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Mirbase:MicroRNA基因组学的工具。

DOI:
10.1093/nar/gkm952
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发表时间:
2008-01
影响因子:
14.9
通讯作者:
Enright, Anton J.
Enright, Anton J.
中科院分区:
生物学2区
文献类型:
--
作者:
Griffiths-Jones, Sam;Saini, Harpreet Kaur;van Dongen, Stijn;Enright, Anton J.

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MiRBase是microRNA(MiRNA)命名、序列数据、注释和目标预测的中央在线存储库。目前的版本(10.0)包含来自58个物种的5071个miRNA基因座,表达5922个不同的成熟miRNA序列:在过去两年中增长了2000多个序列。MiRBase提供了一系列数据来促进miRNA基因组学的研究:所有miRNAs都被映射到它们的基因组坐标。基因组中的miRNA序列簇被突出显示,并且可以使用任何miRNA间距离来定义和检索。描述了miRNA序列与带注释的转录本的重叠,包括蛋白质和非编码。最后,模型生物体中广泛的基因组特征位置的图形视图首次允许预测许多miRNA初级转录本的可能边界。MiRbase可在http://microrna.sanger.ac.uk/.上获得。
miRBase is the central online repository for microRNA (miRNA) nomenclature, sequence data, annotation and target prediction. The current release (10.0) contains 5071 miRNA loci from 58 species, expressing 5922 distinct mature miRNA sequences: a growth of over 2000 sequences in the past 2 years. miRBase provides a range of data to facilitate studies of miRNA genomics: all miRNAs are mapped to their genomic coordinates. Clusters of miRNA sequences in the genome are highlighted, and can be defined and retrieved with any inter-miRNA distance. The overlap of miRNA sequences with annotated transcripts, both protein- and non-coding, are described. Finally, graphical views of the locations of a wide range of genomic features in model organisms allow for the first time the prediction of the likely boundaries of many miRNA primary transcripts. miRBase is available at http://microrna.sanger.ac.uk/.
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发表时间: 2007-05-15
影响因子: 10.5
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