Risk factors for SARS among persons without known contact with SARS patients, Beijing, China.
Risk factors for SARS among persons without known contact with SARS patients, Beijing, China.
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DOI：
10.3201/eid1002.030730
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发表时间：
2004-02
影响因子：
11.8
通讯作者：
Schuchat A
中科院分区：
文献类型：
--
作者：
Wu J;Xu F;Zhou W;Feikin DR;Lin CY;He X;Zhu Z;Liang W;Chin DP;Schuchat A
大多数严重急性呼吸综合征（SARS）病例发生在SARS患者的密切接触者身上。然而，在北京，很大一部分SARS病例发生在没有这种接触的人身上。我们在北京进行了一项病例对照研究，比较了94名无关联的可能SARS患者与281名年龄组和性别匹配的社区对照组的暴露情况。与对照组相比，病例患者更可能患有慢性疾病或去过发热诊所（可能的SARS患者与其他患者分开的诊所），在家外面吃饭，或经常乘坐出租车。口罩的使用具有很强的保护作用。在31例有恢复期（>21天）血清的患者中，26%的患者有SARS相关冠状病毒的免疫球蛋白G。我们的研究发现，临床SARS与发热门诊的就诊有关，这支持了北京关闭感染控制措施差的诊所的策略。我们发现使用口罩可以降低患病风险，这支持了社区使用这一策略。
Most cases of severe acute respiratory syndrome (SARS) have occurred in close contacts of SARS patients. However, in Beijing, a large proportion of SARS cases occurred in persons without such contact. We conducted a case-control study in Beijing that compared exposures of 94 unlinked, probable SARS patients with those of 281 community-based controls matched for age group and sex. Case-patients were more likely than controls to have chronic medical conditions or to have visited fever clinics (clinics at which possible SARS patients were separated from other patients), eaten outside the home, or taken taxis frequently. The use of masks was strongly protective. Among 31 case-patients for whom convalescent-phase (>21 days) sera were available, 26% had immunoglobulin G to SARS-associated coronavirus. Our finding that clinical SARS was associated with visits to fever clinics supports Beijing’s strategy of closing clinics with poor infection-control measures. Our finding that mask use lowered the risk for disease supports the community’s use of this strategy.
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DOI：
10.1016/s0140-6736(03)14121-9
发表时间：
2003-08-16
期刊：
Lancet (London, England)
影响因子：
--
作者：
Ng SK
通讯作者：
Ng SK
DOI：
10.1016/s0140-6736(03)13077-2
发表时间：
2003-04-19
期刊：
Lancet (London, England)
影响因子：
--
作者：
Peiris JS;Lai ST;Poon LL;Guan Y;Yam LY;Lim W;Nicholls J;Yee WK;Yan WW;Cheung MT;Cheng VC;Chan KH;Tsang DN;Yung RW;Ng TK;Yuen KY;SARS study group
通讯作者：
SARS study group
DOI：
10.1001/jama.289.21.joc30885
发表时间：
2003-06-04
影响因子：
120.7
作者：
Booth, CM;Matukas, LM;Detsky, AS
通讯作者：
Detsky, AS
DOI：
10.1016/s0140-6736(03)13410-1
发表时间：
2003-05-24
期刊：
Lancet (London, England)
影响因子：
--
作者：
Donnelly CA;Ghani AC;Leung GM;Hedley AJ;Fraser C;Riley S;Abu-Raddad LJ;Ho LM;Thach TQ;Chau P;Chan KP;Lam TH;Tse LY;Tsang T;Liu SH;Kong JH;Lau EM;Ferguson NM;Anderson RM
通讯作者：
Anderson RM
影响因子：
11.8
作者：
Lingappa JR;McDonald LC;Simone P;Parashar UD
通讯作者：
Parashar UD