Yoga for women with metastatic breast cancer: Results from a pilot study

Yoga for women with metastatic breast cancer: Results from a pilot study
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DOI:
10.1016/j.jpainsymman.2006.08.009
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发表时间:
2007-03-01
影响因子:
4.7
通讯作者:
Miller, Julie M.
Miller, Julie M.
中科院分区:
医学2区
文献类型:
--
作者:
Carson, James W.;Carson, Kimberly M.;Miller, Julie M.

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转移性乳腺癌(MBC)仍然是一种晚期疾病,主要治疗进展缓慢,因此开发有效的姑息干预措施以减少患有这种疾病的妇女在其余生中与癌症相关的症状是至关重要的。这项试点/可行性研究考察了一种新颖的、基于瑜伽的姑息干预,即瑜伽意识计划,对患有MBC的女性样本进行了研究。为期八周的方案包括温和的瑜伽姿势、呼吸练习、冥想、授课演讲和小组交流。在干预前两周和干预的最后两周,使用每日疼痛、疲劳、苦恼、活力、接受和放松的测量来评估结果。13名女性完成了干预(平均年龄=59岁;平均确诊时间=7年;2名非裔美国人,11名高加索人)。在研究期间,四名参与者癌症复发,其他几名参与者的身体状况明显恶化。尽管统计能力较低,但前后多层次结果分析显示,活力和接受度显著增加。对家庭瑜伽练习时长的滞后分析(控制个人平均练习时间和滞后天数的结果水平)表明,在女性练习更多的一天后的第二天,她们体验到的疼痛和疲劳程度明显较低,而活力、接受度和放松程度较高。这些发现支持有必要进一步调查瑜伽意识项目对患有MBC的女性的影响。(C)2007年美国癌症疼痛缓解委员会。爱思唯尔公司出版,版权所有。
Metastatic breast cancer (MBC) remains a terminal illness,for which major treatment advances are slow to appear, and hence it is crucial that effective palliative interventions be developed to reduce the cancer-related symptoms of women with this condition during the remaining years of their lives. This pilot/feasibility study examined a novel, yoga-based palliative intervention, the Yoga of Awareness Program, in a sample of women with MBC. The eight-week protocol included gentle yoga postures, breathing exercises, meditation, didactic presentations, and group interchange. Outcome was assessed using daily measures of pain, fatigue, distress, invigoration, acceptance, and relaxation during two preintervention weeks and the final two weeks of the intervention. Thirteen women completed the intervention (mean age = 59; mean time since diagnosis = 7 years; two African American, 11 Caucasian). During the study, four participants had cancer recurrences, and the physical condition of several others deteriorated noticeably. Despite low statistical power, pre-to-post multilevel outcomes analyses showed significant increases in invigoration and acceptance. Lagged analyses of length of home yoga practice (controlling for individual mean practice time and outcome levels on the lagged days) showed that on the day after a day during which women practiced more, they experienced significantly lower levels of pain and fatigue, and higher levels of invigoration, acceptance, and relaxation. These findings support the need for further investigation of the effects of the Yoga of Awareness Program in women with MBC. (C) 2007 U.S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved.