The effectiveness of vitamin C in preventing and relieving the symptoms of virus-induced respiratory infections
The effectiveness of vitamin C in preventing and relieving the symptoms of virus-induced respiratory infections
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DOI：
10.1016/s0161-4754(99)70005-9
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发表时间：
1999-10-01
影响因子：
1.3
通讯作者：
Jarvis, K
中科院分区：
文献类型：
--
作者：
Gorton, HC;Jarvis, K
背景资料：越来越多的需求，以评估膳食补充剂对特定的健康状况的影响，通过使用一个“重要的科学”的标准，促使本研究的出版。目的：研究大剂量维生素C在预防和缓解感冒和流感症状的效果，在一个测试组与对照组相比。设计：前瞻性，对照研究的学生在技术培训设施。共463名年龄在18岁至32岁之间的学生组成了对照组。实验组或测试组共有252名年龄在18岁至30岁之间的学生。方法：调查人员追踪了该设施1991年测试人群中感冒和Bu症状的报告数量，并与1990年的类似症状报告进行了比较。对照人群。对照人群中报告症状的患者接受止痛药和减充血剂治疗，而试验人群中报告症状的患者在前6小时接受每小时1000 mg维生素C治疗，然后每天3次。试验组中未报告症状的患者也给予1000 mg剂量，每日3次。结果：总体而言，在给予大剂量维生素C后，试验组报告的流感和感冒症状比对照组减少了85%。在试验人群中，在感冒和Au症状出现之前或之后给予大剂量维生素C，与对照组相比，对照组
Background: An ever increasing demand to evaluate the effect of dietary supplements on specific health conditions by use of a "significant scientific" standard has prompted the publication of this study.Objective: To study the effect of megadose Vitamin C in preventing and relieving cold and flu symptoms in a test group compared with a control group.Design: Prospective, controlled study of students in a technical training facility.Subjects: A total of 463 students ranging in age from 18 to 32 years made up the control group. A total of 252 students ranging in age from 18 to 30 years made up the experimental or test group.Method: Investigators tracked the number of reports of cold and Bu symptoms among the 1991 test population of the the facility compared with the reports of like symptoms among the 1990 control population. Those in the control population reporting symptoms were treated with pain relievers and decongestants, whereas those in the test population reporting symptoms were treated with hourly doses of 1000 mg of Vitamin C for the first 6 hours and then 3 times daily thereafter. Those not reporting symptoms in the test group were also administered 1000-mg doses 3 times daily.Results: Overall, reported flu and cold symptoms in the test group decreased 85% compared with the control group after the administration of megadose Vitamin C.Conclusion: Vitamin C in megadoses administered before or after the appearance of cold and Au symptoms relieved and prevented the symptoms in the test population compared with the control group.