Cd2+-selective fluorescence response of TQEN (N,N,N',N')-tetrakis(2-quinolylmethyl)ethylenediamine) derivatives bearing ether oxygen-binding sites
Cd2+-selective fluorescence response of TQEN (N,N,N',N')-tetrakis(2-quinolylmethyl)ethylenediamine) derivatives bearing ether oxygen-binding sites
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带有醚氧结合位点的 TQEN (N,N,N,N)-四(2-喹啉甲基)乙二胺)衍生物的 Cd2 选择性荧光响应
DOI：
10.1039/d2dt02948k
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发表时间：
2022
影响因子：
4
通讯作者：
Takashi Matsuo
中科院分区：
文献类型：
--
作者：
Yuji Mikata;Minori Kaneda;Shizuka Yonemura;Miyu Akedo;Hideo Konno;Takashi Matsuo
通过在四个喹啉环中的一个8位引入甲氧基甲氧基（莫莫）取代基（IZn/ICd = 0.2），TQEN（N，N，N′，N′-四（2-喹啉甲基）乙二胺）对Cd 2+的荧光增强作用由中等的Zn 2+选择性（IZn/ICd = 1.6）变为Cd 2+选择性.因此，8-MOMOTQEN（N-（8-甲氧基甲氧基-2-喹啉基甲基）-N，N′，N′-三（2-喹啉基甲基）乙二胺）不仅显示出高的Cd 2 +-选择性，而且在Cd 2+结合时具有增强的荧光量子产率，并且对Cd 2+检测具有高灵敏度，如通过Cd = 0.065和LOD（检测限）= 19 nM所示。8-MOMOTQEN中莫莫基团的两个氧原子在荧光金属离子选择性中起关键作用，因为相应的羟基（8-OHTQEN）和甲氧基（8-MeOTQEN）衍生物分别导致差的荧光响应和金属选择性。N，N′-双（8-甲氧基-2-喹啉基乙基）-N，N ′-双（2-喹啉基甲基）乙二胺（（8-MeO）2 TQEN）对Zn 2+具有选择性的荧光增强作用（IZn/ICd = 2.2），表明莫莫基团对Cd 2+具有选择性传感作用.
Moderate Zn2+ selectivity over Cd2+ (IZn/ICd = 1.6) in the fluorescence enhancement of TQEN (N,N,N′,N′-tetrakis(2-quinolylmethyl)ethylenediamine) was changed to Cd2+ preference via the introduction of a methoxymethyloxy (MOMO) substituent at the 8-position of one of the four quinoline rings (IZn/ICd = 0.2). Thus, 8-MOMOTQEN (N-(8-methoxymethyloxy-2-quinolylmethyl)-N,N′,N′-tris(2-quinolylmethyl)ethylenediamine) showed not only high Cd2+-selectivity but also an enhanced fluorescence quantum yield upon Cd2+ binding and high sensitivity for Cd2+ detection as shown by ϕCd = 0.065 and LOD (limit of detection) = 19 nM. The two oxygen atoms of the MOMO group in 8-MOMOTQEN play a crucial role in the fluorescent metal-ion selectivity because the corresponding hydroxy (8-OHTQEN) and methoxy (8-MeOTQEN) derivatives resulted in a poor fluorescent response and metal selectivity, respectively. Another N6O2 ligand, N,N′-bis(8-methoxy-2-quinolylethyl)-N,N′-bis(2-quinolylmethyl)ethylenediamine ((8-MeO)2TQEN) exhibited a Zn2+-selective fluorescence enhancement (IZn/ICd = 2.2), indicating the superiority of the MOMO group for the selective sensing of Cd2+.