Optical Assay for Biotechnology and Clinical Diagnosis
Optical Assay for Biotechnology and Clinical Diagnosis
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DOI：
10.1109/tbme.2011.2113348
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发表时间：
2011-08-01
影响因子：
4.6
通讯作者：
Piletsky, Sergey
中科院分区：
文献类型：
--
作者：
Moczko, Ewa;Cauchi, Michael;Piletsky, Sergey
在本文中，我们提出了一种光学诊断分析的混合物组成的环境敏感的荧光染料结合多变量数据分析的生物和临床样品的定量和定性检查。该分析的性能基于对所选荧光染料的光谱的分析，其操作原理类似于电子鼻和电子舌系统。这种方法已成功应用于监测生长的细胞培养物和识别人类胃肠道疾病。
In this paper, we present an optical diagnostic assay consisting of a mixture of environmental-sensitive fluorescent dyes combined with multivariate data analysis for quantitative and qualitative examination of biological and clinical samples. The performance of the assay is based on the analysis of spectrum of the selected fluorescent dyes with the operational principle similar to electronic nose and electronic tongue systems. This approach has been successfully applied for monitoring of growing cell cultures and identification of gastrointestinal diseases in humans.