RESOLUTION OF ENANTIOMERS BY HPLC ON CELLULOSE DERIVATIVES
RESOLUTION OF ENANTIOMERS BY HPLC ON CELLULOSE DERIVATIVES
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DOI：
10.1007/bf02687754
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发表时间：
1984-01-01
期刊：
影响因子：
1.7
通讯作者：
TOGA, Y
中科院分区：
文献类型：
--
作者：
ICHIDA, A;SHIBATA, T;TOGA, Y
合成了各种多糖衍生物，特别是纤维素衍生物，吸附在大孔硅胶上后，用作HPLC光学拆分的手性固定相。在均相条件下合成的三乙酸纤维素（CTA-II）对许多外消旋体表现出手性识别能力。其他纤维素衍生物如纤维素三苯甲酸酯（OB）、纤维素三苯基氨基甲酸酯（OC）、纤维素三苄基醚（OE）和纤维素三肉桂酸酯（OK）也表现出独特的手性识别。在其他多糖衍生物中，三乙酸凝胶多糖也表现出有效的手性识别。
Various polysaccharide derivatives, particularly cellulose derivatives, were synthesized and used as chiral stationary phases for optical resolution by HPLC after being adsorbed on macroporous silica gel. Cellulose triacetate (CTA-II), which was synthesized under homogeneous conditions, showed a chiral recognition ability for many racemates. Other cellulose derivatives such as cellulose tribenzoate (OB), cellulose-trisphenylcarbamate (OC), cellulose tribenzyl ether (OE), and cellulose tricinnamate (OK) also showed unique chiral recognition. Among other polysaccharide derivatives, curdlan triacetate was also exhibited an effective chiral recognition.