Life Cycle of Feline Corpora lutea: Histological and Intraluteal Hormone Analysis
Life Cycle of Feline Corpora lutea: Histological and Intraluteal Hormone Analysis
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DOI：
10.1111/rda.12033
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发表时间：
2012-12-01
影响因子：
1.7
通讯作者：
Dehnhard, M.
中科院分区：
文献类型：
--
作者：
Jewgenow, K.;Amelkina, O.;Dehnhard, M.
内容 黄体 (CL) 是卵巢上的暂时性激素腺，可产生用于维持妊娠的黄体酮 (P4)。它由排卵后残留的卵泡颗粒和卵泡膜细胞发育而来。对于从怀孕和假怀孕猫科动物获得的 CL 中的细胞和激素过程知之甚少。因此，我们的目的是结合我们在家猫和欧亚山猫身上获得的数据来回顾不同生殖阶段猫科动物 CL 的黄体功能。山猫的黄体功能特别令人感兴趣，因为根据重复的超声检查和内分泌检查建议存在产后黄体活动。怀孕和假怀孕家猫的 CL 组织学清楚地反映了黄体功能。排卵后 CL 形成的特点是卵泡膜和颗粒细胞转化为类固醇黄体细胞，并伴有黄体内和循环 P4 水平增加。黄体退化正在稳步进行；从妊娠中期开始，第一个迹象（粗大的空泡形成、非类固醇生成细胞比例增加）就已经在 CL 中可见。
Contents The corpus luteum (CL) is a transient hormone gland on the ovary that produces progesterone (P4) for the maintenance of pregnancy. It develops from residual follicular granulosa and theca cells after ovulation. Very little is known about the cellular and hormonal processes within CLs obtained from pregnant and pseudopregnant felids. Therefore, our aim was to review the luteal function in feline CLs of different reproductive stages in conjunction with our data obtained in domestic cats and Eurasian lynxes. Corpus luteum function in lynxes is of particular interest, as a post-partum luteal activity was suggested based on repeated ultrasonography and endocrine examinations. Histology of CL from pregnant and pseudopregnant domestic cats clearly reflects the luteal function. The formation of the CL after ovulation is characterized by transforming of theca and granulosa cells into steroidogenic luteal cells and is accompanied by increased intraluteal and circulating P4 levels. Luteal regression is steadily progressive; the first signs (coarsed vacuolization, increased proportion of non-steroidogenic cells) are visible already in CL from the second trimester of pregnancy.