Lactate sensitivity in sleeping panic disorder patients and healthy controls.
Lactate sensitivity in sleeping panic disorder patients and healthy controls.
复制标题
睡眠恐慌症患者和健康对照者的乳酸敏感性。
DOI：
10.1016/0006-3223(92)90222-l
复制
发表时间：
1992
影响因子：
10.6
通讯作者：
Kakuma,T
中科院分区：
文献类型：
--
作者：
Koenigsberg,HW;Pollak,CP;Fine,J;Kakuma,T
给予睡眠惊恐障碍（PD）患者乳酸钠输注，以检查惊恐诱导的机制。15例PD患者和12例正常对照者（年龄20-59岁）在睡眠时分别用1.0mol/L乳酸钠（SL）或5%葡萄糖和0.9%生理盐水灌胃，测定觉醒反应。SL没有引发恐慌发作从睡眠中的任何SS，但PD的SS被发现比控制SL的唤醒属性更敏感。据推测，PD Ss比正常对照组睡眠更浅，更容易被任何刺激唤醒。（PsycInfo数据库记录（c）2022阿帕，保留所有权利）
Administered sodium lactate infusions to sleeping panic disorder (PD) patients to examine the mechanism of panic induction. Changes in median sleep stage and frequency of waking measured the arousal response in 15 PD patients and 12 normal controls (aged 20–59 yrs) infused during sleep with either 1.0 mol/L sodium lactate (SL) or 5% dextrose and 0.9% saline. SL did not trigger panic attacks from sleep in any Ss, but PD Ss were found to be more sensitive than controls to the arousogenic properties of SL. It was hypothesized that PD Ss were lighter sleepers than normal controls and more prone to be aroused by any stimulus.(PsycInfo Database Record (c) 2022 APA, all rights reserved)