PEROXYNITRITE: A MEDIATOR OF INCREASED MICROVASCULAR PERMEABILITY?

PEROXYNITRITE: A MEDIATOR OF INCREASED MICROVASCULAR PERMEABILITY?
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过氧亚硝酸盐:增加微血管渗透性的介质?

DOI:
10.1111/j.1440-1681.1997.tb02709.x
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发表时间:
1997
影响因子:
2.9
通讯作者:
Susan D. Brain
Susan D. Brain
中科院分区:
医学4区
文献类型:
--
作者:
S. Greenacre;Victoria Ridger;P. Wilsoncroft;Susan D. Brain

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1.诱导型一氧化氮合酶(iNOS)的表达增加和随后的炎症部位一氧化氮(NO)水平升高,导致过氧亚硝酸盐(超氧化物和NO的反应产物)参与促炎过程的建议。本研究探讨了过氧亚硝基阴离子诱导大鼠皮肤微血管水肿形成的能力。
1. Increased expression of inducible nitric oxide synthase (iNOS) and subsequent elevation of nitric oxide (NO) levels at inflammatory sites have led to the suggestion that peroxynitrite (the reaction product of superoxide and NO) is involved in proinflammatory processes. The present study has investigated the ability of peroxynitrite to induce oedema formation in the rat cutaneous microvasculature.
DOI: 10.1042/bst0210330
发表时间: 1993-05-01
影响因子: 3.9
作者:
BECKMAN, JS;CROW, JP
通讯作者: CROW, JP