Sustained facial muscle activity during REM sleep and its correlation with depression.

Sustained facial muscle activity during REM sleep and its correlation with depression.
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快速眼动睡眠期间的持续面部肌肉活动及其与抑郁的相关性。

DOI:
10.1016/0165-0327(95)00065-8
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发表时间:
1995
影响因子:
6.6
通讯作者:
S. James
S. James
中科院分区:
医学2区
文献类型:
--
作者:
M. Perlis;D. Giles;G. M. Fleming;S. Drummond;S. James

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最近,我们提出,在REM睡眠期间,认知激活和唤醒减弱的耦合可能具有情绪调节作用。相反,快速眼动睡眠期间的觉醒增加可能与情绪失调有关。在本文中,脱敏模型进行了描述,并提出了数据之间的关联运动活动在REM睡眠,清醒和抑郁症的严重程度。从23名抑郁症患者中获得运动活动睡眠EEG数据和两种抑郁严重程度测量(BDI和HRSD)。BDI分数仅在REM睡眠期间与运动活动显著相关。HRSD评分仅在安静清醒时与运动活动相关。这些发现与理论观点一致,即REM睡眠期间唤醒机制的失调可能会促进抑郁发作期间的情绪障碍。
Recently, we proposed that the coupling of cognitive activation and diminished arousal during REM sleep may have a mood regulating effect. Conversely, increased arousal during REM sleep may be associated with mood dysregulation. In this paper, the desensitization model is described, and data are presented on the association between motor activity during REM sleep, wakefulness and severity of depression. Motor activity sleep EEG data and two measures of depressive severity (BDI and HRSD) were obtained from 23 depressed patients. BDI scores were significantly correlated with motor activity only during REM sleep. HRSD scores were correlated with motor activity only during quiet wakefulness. These findings are consistent with the theoretical perspective that dysregulation in arousal mechanisms during REM sleep may promote mood disturbance during the depressive episode.
DOI: 10.1001/archpsyc.1985.01790310068009
发表时间: 1985
影响因子: --
作者:
Kupfer,DJ;Ulrich,RF;Coble,PA;Jarrett,DB;Grochocinski,VJ;Doman,J;Matthews,G;Borbély,AA
通讯作者: Borbély,AA