Randomized controlled study of in-hospital exercise training programs in children with cystic fibrosis
Randomized controlled study of in-hospital exercise training programs in children with cystic fibrosis
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DOI：
10.1002/ppul.10015
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发表时间：
2002-03-01
影响因子：
3.1
通讯作者：
van Asperen, PP
中科院分区：
文献类型：
--
作者：
Selvadurai, HC;Blimkie, CJ;van Asperen, PP
本研究的目的是比较因并发肺部感染而入院的囊性纤维化 (CF) 儿童与对照组的有氧训练和阻力训练。受试者在入院第一天被随机分为三组。使用四个部位（二头肌、三头肌、肩胛下肌和髂嵴）的皮褶厚度计算去脂质量 (FFM)。入院 36 小时内进行肺功能测试，出院时重复进行一次，出院后 1 个月再次进行一次。所有受试者均使用改良的布鲁斯方案进行增量跑步机运动测试。使用 Cybex 测力计测量下肢力量。如之前报道的那样，使用幸福质量量表对生活质量进行了评估。使用 7 天的活动日记测量活动水平，受试者还在臀部佩戴加速计。三组之间的疾病严重程度和住院时间没有显着差异。根据医生的决定，所有三组的受试者均接受静脉注射抗生素和营养补充。随机分配到有氧训练组的儿童每周参加五次有氧活动，每次持续 30 分钟。随机分配到阻力训练组的孩子们在分级阻力机上锻炼上肢和下肢。对照组的受试者接受标准的胸部物理治疗。我们的研究表明，接受有氧训练的儿童的峰值有氧能力、活动水平和生活质量明显优于接受阻力训练计划的儿童。接受阻力训练的儿童比接受有氧训练的儿童有更好的体重增加（总质量以及去脂质量）、肺功能和腿部力量。有氧训练和阻力训练的结合可能是最好的训练计划，未来有研究评估 CF 患者的最佳训练计划。 (C) 2002 Wiley-Liss, Inc.
The aim of this study was to compare aerobic and resistance training in children with cystic fibrosis (CF) admitted to hospital with an intercurrent pulmonary infection with a control group. The subjects were randomized into three groups on the first day of admission. The fat-free mass (FFM) was calculated, using the skin fold thickness from four sites (biceps, triceps, subscapular, and iliac crest). Pulmonary function tests were performed within 36 hr of admission and repeated on discharge from the hospital, and again at 1 month after discharge. All subjects performed an incremental treadmill exercise test, using a modified Bruce protocol. Lower limb strength was measured using a Cybex dynamometer. An assessment of quality of life was made using the Quality of Well Being Scale, as previously reported. Activity levels were measured using a 7-day activity diary, and subjects also wore an accelerometer on their hips. There were no significant differences between the three groups in terms of disease severity, and length of stay in hospital. Subjects in all three groups received intravenous antibiotics and nutritional supplementation as determined by the physician. Children randomized to the aerobic training group participated in aerobic activities for five sessions, each of 30-min duration, a week. The children randomized to the resistance training group exercised both upper and lower limbs against a graded resistance machine. Subjects in the control group received standard chest physiotherapy.Our study demonstrated that children who received aerobic training had significantly better peak aerobic capacity, activity levels, and quality of life than children who received the resistance training program. Children who received resistance training had better weight gain (total mass, as well as fat-free mass), lung function, and leg strength than children who received aerobic training.A combination of aerobic and resistance training may be the best training program, and future studies to assess optimal training programs for CF patients are indicated. (C) 2002 Wiley-Liss, Inc.