Ontogeny of amicable social behavior in the mouse: gender differences and ongoing isolation outcomes.
Ontogeny of amicable social behavior in the mouse: gender differences and ongoing isolation outcomes.
复制标题
小鼠友好社会行为的个体发育：性别差异和持续的孤立结果。
DOI：
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发表时间：
1993
影响因子：
2.2
通讯作者：
Enrico Alleva
中科院分区：
文献类型：
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作者：
M. Terranova;G. Laviola;Enrico Alleva
在发育期间（出生后第23-47天），对雄性和雌性远系杂交CD-1小鼠的行为库进行了表征。为了评估饲养条件的影响，一半的受试者在断奶（第21天）时单独饲养（IC），而其余的小鼠则与同性同胞成对饲养（PC）。22个行为项目的发生率进行了评分，在9个社会的遭遇，相隔3天，对不熟悉的同性和相同条件的动物之间。单独圈养的小鼠比成对的受试者更参与单独游戏和社会互动（亲和，调查和征求行为），而对非社会行为（探索，逃避或维护活动）不太感兴趣。社会行为要素的日增长是明显的，在23-32日龄的亲和行为的高峰。对于性别差异，与大鼠的数据相比，一个显着的女性主导的社会和嬉戏behaviors. Overall，这些研究结果清楚地表明，发育中的小鼠在配对遇到的行为剧目强烈受两个主题的性别和住房条件，他们正在经历。
The behavioral repertoire of male and female outbred CD-1 mice was characterized during development (postnatal Days 23-47). To assess the effects of the rearing condition, half of the subjects were individually housed (IC) at weaning (Day 21), while the remaining mice were housed in pairs (PC) of same-sex siblings. The occurrence of 22 behavioral items was scored during nine social encounters, 3 days apart, between pairs of unfamiliar same-sex and same-condition animals. Individually housed mice were much more involved than paired subjects in solitary play and social interactions (affiliative, investigative, and soliciting behaviors), while less interested in nonsocial behaviors (exploration, and escape-oriented or maintenance activities). An over-days increment for elements of social behavior was evident, with a peak of affiliative behavior at 23-32 days of age. For gender differences, in contrast with rat data, a marked female primacy in both social and playful behaviors was found. Overall, these findings clearly indicate that the behavioral repertoire of developing mice during paired encounters is strongly affected by both the sex of the subjects and the housing condition they are experiencing.