Repair of potentially lethal radiation damage in confluent and non-confluent cultures of human hybrid cells.
Repair of potentially lethal radiation damage in confluent and non-confluent cultures of human hybrid cells.
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修复人类杂交细胞汇合和非汇合培养物中潜在致命的辐射损伤。
DOI：
10.1080/09553008514552621
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
Stanbridge,EJ
中科院分区：
文献类型：
--
作者：
Sun,C;Redpath,JL;Colman,M;Stanbridge,EJ
本文研究了γ射线照射后人皮肤成纤维细胞× HeLa细胞及其致瘤分离物的潜在致死性损伤（PLDR）的修复与照射时细胞密度和照射后修复期的关系。数据显示PLDR发生在两种细胞系的非融合和融合培养物中。此外，有证据表明PLDR的程度取决于细胞密度，细胞-细胞接触可能是这方面的一个重要因素。
The repair of potentially lethal damage (PLDR) in a gamma-irradiated human hybrid cell line (skin fibroblast × HeLa) and its tumourigenic segregant has been studied as a function of cell density at the time of irradiation and during the post-irradiation repair period. The data show that PLDR occurs in both non-confluent and confluent cultures of both cell lines. Furthermore, there is evidence that the extent of PLDR is dependent on cell density and that cell-cell contact may be an important factor in this regard.