Multiple scattering in optical coherence tomography. I. Investigation and modeling
Multiple scattering in optical coherence tomography. I. Investigation and modeling
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DOI：
10.1364/josaa.22.001369
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发表时间：
2005-07-01
影响因子：
1.9
通讯作者：
Lambelet, P
中科院分区：
文献类型：
--
作者：
Karamata, B;Laubscher, M;Lambelet, P
提出了一种考虑多次散射的光学相干层析成像(OCT)新模型。理论分析和实验研究表明，在OCT中，尽管有多次散射，但样品的后向散射场通常是空间相干的，所产生的与参考场的干涉信号相对于测量时间是平稳的。在这一结果的基础上，我们将OCT信号建模为具有随机相位变元的空间相干场的总和-在测量时间内是恒定的-由多次散射引起。我们根据统计光学的经典结果和蒙特卡罗模拟计算了这种随机信号的平均值。由我们的模型预测的OCT信号与由微球水悬浮液覆盖的反射镜组成的样品的深度扫描测量非常一致。我们讨论了基于扩展惠更斯-菲涅耳原理的其他综合OCT模型，这些模型建立在部分相干干涉场的假设下。(C)2005年美国光学学会。
We present a new model of optical coherence tomography (OCT) taking into account multiple scattering. A theoretical analysis and experimental investigation reveals that in OCT, despite multiple scattering, the field backscattered from the sample is generally spatially coherent and that the resulting interference signal with the reference field is stationary relative to measurement time. On the basis of this result, we model an OCT signal as a sum of spatially coherent fields with random-phase arguments-constant during measurement time-caused by multiple scattering. We calculate the mean of such a random signal from classical results of statistical optics and a Monte Carlo simulation. OCT signals predicted by our model are in very good agreement with a depth scan measurement of a sample consisting of a mirror covered with an aqueous suspension of microspheres. We discuss other comprehensive OCT models based on the extended Huygens-Fresnel principle, which rest on the assumption of partially coherent interfering fields. (C) 2005 Optical Society of America.