Enantioselective total synthesis of (+)-galbulin via organocatalytic domino Michael-Michael-aldol condensation

Enantioselective total synthesis of (+)-galbulin via organocatalytic domino Michael-Michael-aldol condensation
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DOI:
10.1039/c2cc16682h
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发表时间:
2012-01-01
影响因子:
4.9
通讯作者:
Lee, Gene-Hsiang
Lee, Gene-Hsiang
中科院分区:
化学2区
文献类型:
--
作者:
Hong, Bor-Cherng;Hsu, Che-Sheng;Lee, Gene-Hsiang

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以有机催化的多米诺Michael-Michael-Aldol缩合反应和有机催化的动力学拆分为关键步骤,实现了(+)-galbulin的对映选择性合成。
A concise and practical enantioselective synthesis of (+)-galbulin has been achieved using organocatalytic domino Michael-Michael-aldol condensation and organocatalytic kinetic resolution as the key steps.