Response to Letter to the Editor regarding "Effects of respiratory training on heart rate variability and baroreflex sensitivity in individuals with chronic spinal cord injury".
Response to Letter to the Editor regarding "Effects of respiratory training on heart rate variability and baroreflex sensitivity in individuals with chronic spinal cord injury".
复制标题
回复关于“呼吸训练对慢性脊髓损伤个体心率变异性和压力反射敏感性的影响”的致编辑信。
DOI：
10.1016/j.apmr.2018.01.001
复制
发表时间：
2018
影响因子：
4.3
通讯作者：
Ovechkin,AlexanderV
中科院分区：
文献类型：
--
作者：
LeggDitterline,BonnieE;Asian,SevdaC;Randall,DavidC;Harkema,SusanJ;Castillo,Camilo;Ovechkin,AlexanderV
报告的研究的目的是调查我们最初的交互呼吸训练方法是否可以影响压力反射功能，而这种功能在一般SCI人群中通常是失调的。研究组有意纳入了不同程度和严重程度损伤的参与者，这些参与者具有各种不同的心血管功能状态。由于呼吸运动功能不是主要的关注点，最大气道压力值没有报道，但当我们在未来的出版物中讨论与呼吸运动控制相关的具体机制时，我们会报道，正如所承认的那样，干预组和对照组的参与者样本在功能上是异质的，有各种各样的损伤水平和严重程度。这就是为什么为了控制组内的变异性，使用多变量线性回归模型来检验显著性。在这种情况下，简单的学生t检验是不合适的。表3阐明了损伤水平和严重程度对训练后肺功能、压力反射和心率变异性结果变化的作用。
The objective of the reported study was to investigate if our original reciprocal respiratory training approach, already reported to be effective in improving blood pressure regulation in individuals with SCI-induced orthostatic hypotension2, can affect baroreflex function which is often deconditioned in the general SCI population. Study groups intentionally included participants with different levels and severity of injury with a variety of respiratorycardiovascular functional states. Since respiratory motor function was not the primary point of interest, maximum airway pressure values were not reported, but will be when we address specific mechanisms related to respiratory motor control in future publications.As acknowledged, the sample of participants in the intervention and control groups was functionally heterogeneous, with a variety of levels and severity of injury. That is why, in order to control for variability within groups, a multivariate linear regression model was used to test for significance. A simple Student’s t-test is not appropriate in this case. The role played by level and severity of injury on changes in pulmonary function, baroreflex, and heart rate variability outcomes after training was elucidated in Table 3.