Infant malnutrition predicts conduct problems in adolescents.
Infant malnutrition predicts conduct problems in adolescents.
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DOI：
10.1179/1476830512y.0000000012
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发表时间：
2012-07
影响因子：
3.6
通讯作者：
Fitzmaurice G
中科院分区：
文献类型：
--
作者：
Galler JR;Bryce CP;Waber DP;Hock RS;Harrison R;Eaglesfield GD;Fitzmaurice G
本研究的目的是比较行为问题的患病率在一个有据可查的样本巴巴多斯青少年营养不良的婴儿和人口比较组，并确定在何种程度上认知障碍和环境因素占这种关联。使用76项自我报告量表对56名巴巴多斯青年（11 - 17岁）的行为症状进行了评估，这些青年的蛋白质-能量营养不良（PEM）史仅限于生命的第一年和60名健康的同学。在儿童期和青少年期的3个时间点进行纵向和横断面多元回归分析进行组间比较。自我报告的行为问题在以前营养不良的青少年中更普遍（P <0.01）。儿童智商和家庭环境的情况下，部分调解与营养不良。教师报告的课堂行为在较早的年龄显着相关的青少年行为问题，确认通过童年和青春期的行为问题的连续性。自我报告的行为问题在有幼儿营养不良史的儿童和青少年中升高。后来的脆弱性增加的行为问题似乎是介导的更近端的神经行为的影响，营养不良的认知功能和不利的条件，在早期的家庭环境。
The purpose of this study was to compare the prevalence of conduct problems in a well-documented sample of Barbadian adolescents malnourished as infants and a demographic comparison group and to determine the extent to which cognitive impairment and environmental factors account for this association. Behavioral symptoms were assessed using a 76-item self-report scale in 56 Barbadian youth (11–17 years of age) with histories of protein–energy malnutrition (PEM) limited to the first year of life and 60 healthy classmates. Group comparisons were carried out by longitudinal and cross-sectional multiple regression analyses at 3 time points in childhood and adolescence. Self-reported conduct problems were more prevalent among previously malnourished youth (P < 0.01). Childhood IQ and home environmental circumstances partially mediated the association with malnutrition. Teacher-reported classroom behaviors at earlier ages were significantly correlated with youth conduct problems, confirming the continuity of conduct problems through childhood and adolescence. Self-reported conduct problems are elevated in children and adolescents with histories of early childhood malnutrition. Later vulnerability to increased conduct problems appears to be mediated by the more proximal neurobehavioral effects of the malnutrition on cognitive function and by adverse conditions in the early home environment.