A 3-YEAR DIAGNOSTIC AND EPIDEMIOLOGICAL-STUDY ON VIRAL INFANTILE DIARRHEA IN ROME
A 3-YEAR DIAGNOSTIC AND EPIDEMIOLOGICAL-STUDY ON VIRAL INFANTILE DIARRHEA IN ROME
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DOI：
10.1017/s0950268800067443
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发表时间：
1988-04-01
影响因子：
4.2
通讯作者：
VELLA, S
中科院分区：
文献类型：
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作者：
DONELLI, G;RUGGERI, FM;VELLA, S
1982年1月至1984年12月期间，罗马因急性腹泻住院的573名儿童中，有168名（29.3%）被证实感染轮状病毒。这些感染的实验室诊断是通过透射电子显微镜和酶免疫分析技术进行的，总体一致性为91.3%。 36 名患者（6.4%）的粪便中检测到星状病毒和小圆形病毒。 1982年，轮状病毒阳性患者集中在冬季和次年春季，而在接下来的几年中，全年都有病例记录。 1982年、1983年和1984年轮状病毒感染患者的中位年龄分别为17个月、10个月和11.5个月。此外，与前几年和随后几年收治的病例相比，1983 年收治的轮状病毒阳性病例数量较少。据推测，1982年上半年轮状病毒的流行在人群中引发了群体免疫。
Rotavirus infection was demonstrated in 168 (29.3%) of 573 children hospitalized for acute diarrhoea in Rome between January 1982 and December 1984. Laboratory diagnosis of these infections was made by transmission electron microscopy and enzyme immunoassay techniques with an overall agreement of 91.3%. Astroviruses and small round viruses were detected in the faeces of 36 patients (6.4%). Whereas in 1982 rotavirus positive patients were clustered in the winter and following spring, in the following years cases were recorded all year round. The median age of patients with rotavirus infections was 17, 10 and 11.5 months in 1982, 1983 and 1984, respectively. In addition, a smaller number of rotavirus positive cases were admitted in 1983 when compared to those admitted during the previous as well as the subsequent years. It is suggested that a herd immunity was induced in the population by epidemic spread of rotavirus in the first half of 1982.