Neural oscillations associated with item and temporal order maintenance in working memory.
Neural oscillations associated with item and temporal order maintenance in working memory.
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DOI：
10.1523/jneurosci.0828-11.2011
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发表时间：
2011-07-27
期刊：
影响因子：
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通讯作者：
Ranganath C
中科院分区：
文献类型：
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作者：
Hsieh LT;Ekstrom AD;Ranganath C
在工作记忆中保持信息的能力不仅需要主动保持关于特定项目的信息，而且需要保持项目出现的时间顺序。虽然许多研究已经探讨了项目维持的神经机制，但对工作记忆中时间顺序维持的神经机制知之甚少。在这里，我们使用脑电图（EEG）比较WM任务，需要维护的项目或时间顺序信息的神经振荡。行为结果显示，准确性和反应时间是可比的两种条件下，这表明任务难度之间的项目和时序工作记忆任务相匹配。EEG分析表明，θ（5 - 7 Hz）的前额叶网站的振荡增加，在时间秩序的维护，而α振荡（9 - 12 Hz）的后顶叶和枕叶外侧网站的项目维护期间增加。额叶theta增强主要是明显的顺序WM任务的高性能，而后α增强主要是明显的项目WM任务的高性能。这些结果支持的想法，额叶θ和后α振荡的差异相关的项目和时间顺序信息的维护。
The ability to retain information in working memory (WM) requires not only the active maintenance of information about specific items, but also the temporal order in which the items appeared. Although many studies have investigated the neural mechanisms of item maintenance, little is known about the neural mechanisms of temporal order maintenance in WM. Here, we used electroencephalography (EEG) to compare neural oscillations during WM tasks that required maintenance of item or temporal order information. Behavioral results revealed that accuracy and reaction times were comparable between the two conditions, suggesting that task difficulty was matched between the item and temporal order WM tasks. EEG analyses indicated that theta (5–7 Hz) oscillations over prefrontal sites were increased during temporal order maintenance, whereas alpha oscillations (9–12 Hz) over posterior parietal and lateral occipital sites were increased during item maintenance. The frontal theta enhancement was primarily evident in high performers on the order WM task, whereas the posterior alpha enhancement was primarily evident in high performers on the item WM task. These results support the idea that frontal theta and posterior alpha oscillations are differentially related to maintenance of item and temporal order information.