Biogenic synthesis enhanced structural, morphological, magnetic and optical properties of zinc ferrite nanoparticles for moderate hyperthermia applications
Biogenic synthesis enhanced structural, morphological, magnetic and optical properties of zinc ferrite nanoparticles for moderate hyperthermia applications
复制标题
DOI：
10.1007/s11051-021-05149-w
复制
发表时间：
2021-02-01
影响因子：
2.5
通讯作者：
Ezema, Fabian, I
中科院分区：
文献类型：
--
作者：
Aisida, Samson O.;Ali, Awais;Ezema, Fabian, I
采用洋葱水提取物作为还原剂，优化了铁酸锌纳米颗粒的性质，并采用生物合成法制备了铁酸锌纳米颗粒。XRD、SEM、DRS、拉曼和VSM的各种表征结果清楚地表明，配制的ZFNP是具有11-15 nm范围内的微晶尺寸的单相。对于所有粒径在34-52 nm范围内的样品，观察到球形形态。所有样品均表现出超顺磁性行为，饱和磁化强度降低。制备的ZFNP用于在180 Oe施加场和425 Hz下的热疗应用中的自加热分析。它在治疗温度范围内产生足够的热量以达到居里温度。由于ZFNP具有良好的生物相容性，居里温度适中，SAR值在治疗范围内，因此ZFNP具有良好的热疗应用前景，副作用较小。所配制的纳米颗粒进一步拓宽了热疗应用的视野，其在300秒内具有无害的方案。
A biogenic protocol has been adopted for the formulation of zinc ferrite nanoparticles (ZFNPs) using an aqueous extract of Allium cepa (AC) as a reducing agent for the optimization of its properties. The various characterization results from XRD, SEM, DRS, Raman, and VSM clearly showed that the formulated ZFNP was a single phase with crystallite size in the range of 11-15 nm. A spherical morphology was observed for all the samples with particle size in the range of 34-52 nm. All the samples showed a superparamagnetic behavior with reduced saturation magnetization. The ZFNPs prepared were used for self-heating analysis in hyperthermia applications at 180 Oe applied field and 425 Hz. It produced enough heating within the therapeutic temperature to attain the Curie temperature. The ZFNP formulated is auspicious for hyperthermia applications with less side effect owing to their biocompatibility, moderate Curie temperature, and SAR value within the therapeutic range. The formulated nanoparticles have further broadened the horizon of hyperthermia therapeutic applications with an innocuous protocol within 300 s.