A 2-year retrospective review of vial sharing options for the compounding of cytotoxics
A 2-year retrospective review of vial sharing options for the compounding of cytotoxics
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DOI：
10.1136/ejhpharm-2014-000547
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发表时间：
2015-05-01
影响因子：
1.7
通讯作者：
Smith, Rufus S. V.
中科院分区：
文献类型：
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作者：
Smith, Rufus S. V.
目的瓶共用操作给无菌配药带来风险。本审查旨在量化承担这一额外风险所能获得的财务收益。方法通过对某综合地区医院2年时间内的所有药物复合剂量进行统计，可以计算出使用的药瓶数以及每种药物的浪费量。这样就有可能使用复合药物剂量，并针对四种不同的小瓶共享选项对数据进行建模。选项1为不共享，选项2为一天共享，选项3为周一至周五共享，选项4为7天滚动共享。选择3和4考虑到每瓶增加的消耗品成本。结果在2年的时间里，滚动7天的瓶子共享实践显示出相当大的成本节约。这种节省在所有复合药物中并不一致，一些高成本小容量药物由于滚动7天共用小瓶做法而导致额外成本。结论共用小瓶可降低耗材成本，并可通过选择共用小瓶的药物进一步提高成本。
Objectives Vial sharing practices introduce risk to aseptic compounding. This review aims to quantify the financial gain that can be achieved from taking on this additional risk.Method By looking at all drug doses compounded over a 2-year period at a general district hospital, it has been possible to calculate the number of vials used along with the amount of each drug that was wasted. From there it was possible to use the drug doses compounded and model this data against four different options around vial sharing. Option 1 was for no vial sharing, option 2 was for vial sharing on a single day, option 3 was for vial sharing Monday to Friday and option 4 was for vial sharing on a rolling 7-day basis. Options 3 and 4 allowed for an added consumable cost per vial.Results Over the 2-year period, a rolling 7-day vial sharing practice showed considerable cost savings. This saving was not uniform across all drugs compounded, with some high-cost low-volume drugs resulting in additional cost from a rolling 7-day vial sharing practice.Conclusions Vial sharing is cost effective against increased consumable costs and can be further enhanced by selecting the drugs to use vial sharing for.