Measurement of tissue optical properties by the use of oblique-incidence optical fiber reflectometry
Measurement of tissue optical properties by the use of oblique-incidence optical fiber reflectometry
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DOI：
10.1364/ao.36.000136
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发表时间：
1997-01-01
期刊：
影响因子：
1.9
通讯作者：
Tittel, FK
中科院分区：
文献类型：
--
作者：
Lin, SP;Wang, LH;Tittel, FK
基于光纤的斜入射反射法是测量半无限浑浊介质吸收系数和折合散射系数Mu(A)和Mu‘(S)的一种简单而准确的方法。倾斜入射灯光会产生漫反射的空间分布，而不是以灯光入射点为中心。漫反射中心的移动量与介质的漫射长度D直接相关。我们研制了一种光纤探头，可以斜向传输光，并采样漫反射的相对轮廓，不需要以绝对单位进行测量。根据该分布，可以测量D，对有效衰减系数Mu(Ef)进行曲线拟合，然后计算Mu(A)和Mu‘(S)。该方法用蒙特卡罗模拟进行了验证，并在组织模型上进行了测试。我们对D和Mu(Ef)的测量有大约5%的精度，因此对于Mu(A)和Mu‘(S)，我们分别有10%和5%的精度。(C)1997年美国光学学会
Fiber-optic-based oblique-incidence reflectometry is a simple and accurate method for measuring the absorption and reduced scattering coefficients mu(a) and mu'(s) of semi-infinite turbid media. Obliquely incident light produces a spatial distribution of diffuse reflectance that is not centered about the point of Light entry. The amount of shift in the center of diffuse reflectance is directly related to the medium's diffusion length D. we developed a fiber-optic probe to deliver light obliquely and sample the relative profile of diffuse reflectance, Measurement in absolute units is not necessary. From the profile, it was possible to measure D, perform a curve fit for the effective attenuation coefficient mu(eff) and then calculate mu(a) and mu'(s). This method was verified with Monte Carlo simulations and tested on tissue phantoms. Our measurements of D and mu(eff) had an accuracy of approximately 5%, thus giving us 10% and 5% accuracy for mu(a) and mu'(s), respectively. (C) 1997 Optical Society of America