Two Spirostan Steroid Glycoside Fatty Esters from Dioscorea cayenensis
Two Spirostan Steroid Glycoside Fatty Esters from Dioscorea cayenensis
复制标题
DOI：
10.1177/1934578x1300800311
复制
发表时间：
2013-03
影响因子：
1.8
通讯作者：
Z. Ali;T. Smillie;I. Khan
中科院分区：
文献类型：
--
作者：
Z. Ali;T. Smillie;I. Khan
从山药的甲醇提取物中分离得到2个新的脂肪酸螺环甾苷酯，即前体棕榈酸酯(1)和前体素III亚油酸酯(2)。该提取物还产生了7个已知的螺杆菌和呋喃类固醇糖苷(3-9)。新化合物的结构经化学和波谱方法确定为(25R)-螺-5-烯-3-O-α-L-rhamnopyranosyl-(1→2)-[6-O-palmitoyl]-O-β-D-glucopyranoside(1)和(25R)-螺-5-烯-3-O-α-L-rhamnopyranosyl-(1→2)-[6-O-linoleoyl]-O-β-D-glucopyranoside(2)。已知化合物分别鉴定为：前体素III(3)、薯蓣皂苷(4)、胡萝卜素(5)、天冬青(6)、薄荷西林(7)、原山药皂苷(8)和甲基原山药皂苷(9)。
Two new fatty acid-spirostan steroid glycoside esters, progenin III palmitate (1) and progenin III linoleate (2), were isolated from the MeOH extract of Dioscorea cayenensis rhizomes. The extract also yielded seven previously known spirostan and furostan steroid glycosides (3-9). The structures of the new compounds were established as (25R)-spirost-5-en-3β-yl O-α-L-rhamnopyranosyl-(1→2)-[6-O-palmitoyl]-O-β-D-glucopyranoside (1) and (25R)-spirost-5-en-3β-yl O-α-L-rhamnopyranosyl-(1→2)-[6-O-linoleoyl]-O-β-D-glucopyranoside (2) by chemical and spectroscopic methods, including 1D and 2D NMR. The known compounds were identified as progenin III (3), dioscin (4), deltonin (5), asperin (6), gracillin (7), protodioscin (8)], and methyl protodioscin (9).