Trypsin inhibition by tapeworms: antienzyme secretion or pH adjustment?
Trypsin inhibition by tapeworms: antienzyme secretion or pH adjustment?
复制标题
绦虫抑制胰蛋白酶：抗酶分泌还是 pH 调节？
作者：
G. L. Uglem;J. Just
The tapeworm Hymenolepis diminuta releases proteins that inhibit trypsin activity. These proteins may be either antienzymes or nonspecific macromolecules that interfere with trypsin. Saline solutions with initial pH values ranging from 5.5 to 10.0 were all acidified to pH 5.0 by tapeworms. If the initial pH was lower than 5.0, it was raised. Because trypsin activity is inhibited at pH 5.0, this intestinal parasite can protect itself from digestion by regulating its environmental pH or releasing trypsin inhibitors, or both.
