IMMEDIATE AND LONG-TERM SYMPTOMATIC COURSE OF PSYCHIATRIC OUTPATIENTS.
IMMEDIATE AND LONG-TERM SYMPTOMATIC COURSE OF PSYCHIATRIC OUTPATIENTS.
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精神病门诊患者的近期和长期症状过程。
DOI：
10.1176/ajp.120.5.429
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发表时间：
1963
期刊：
影响因子：
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通讯作者：
S. Imber
中科院分区：
文献类型：
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作者：
J. D. Frank;E. Nash;A. Stone;S. Imber
两组共109名精神科门诊患者被给予安慰剂，并在服用安慰剂1周和2周后立即观察到对他们报告的痛苦水平的影响。两个人群中的患者在接受安慰剂之前和之后都接受了特殊的测试和测量。每组中超过一半的患者分别在3年和2年后重新接受检查，其中一些患者再次接受安慰剂治疗。在两组中，无论使用的标准或时间间隔，更大比例的患者报告改善比报告恶化。在第一次访谈期间，在安慰剂给药前后，平均不适评分急剧下降，然后趋于增加，但没有回到初始水平。安慰剂维持治疗并未增加效应。改善的程度与最初报告的痛苦程度有关，焦虑和抑郁症状的改善程度高于躯体症状。患者的反应几乎没有一致性。
Two populations of psychiatric outpatients totalling 109 were given placebos and the effect on their reported level of distress noted immediately and after 1 and 2 weeks on the placebo. Patients in both populations received special tests and measures before and after receiving placebo. Over half the patients in each group were re-examined after 3 and 2 years respectively, at which time some again received a placebo. In both groups, whatever the criterion used or the time interval, a greater proportion of patients reported improvement than reported getting worse. The mean discomfort score dropped sharply during the first interview, before as well as after administration of the placebo, then tended to increase, but not back to the initial level. Maintenance on placebo did not increase the effect. The amount of improvement was related to amount of distress reported initially, and symptoms of anxiety and depression showed more improvement than somatic ones. Patients showed little consistency in their responsi...