Specific keynote: Hereditary ovarian cancer: What we know

Specific keynote: Hereditary ovarian cancer: What we know
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DOI:
10.1006/gyno.2002.6674
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发表时间:
2003-01-01
影响因子:
4.7
通讯作者:
Boyd, J
Boyd, J
中科院分区:
医学2区
文献类型:
--
作者:
Boyd, J

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在过去的几年中,基本上所有表现的高渗透性,常染色体显性遗传易感性卵巢癌的分子遗传基础已被完全阐明。本综述的目的是提供一个简明扼要的总结,这些信息,特别强调临床意义。演讲将采取非专家和患者最常问的具体问题的形式,目的是为读者提供最新的答案和对遗传性卵巢癌基本原理的广泛理解。
Over the past several years, the molecular genetic basis of essentially all manifestations of highly penetrant, autosomal dominant hereditary predisposition to ovarian cancer has been completely elucidated. The purpose of this overview is to provide a succinct summary of this information, with particular emphasis on clinical implications. The presentation will take the form of specific questions that are most frequently asked by nonspecialists and patients, with the goal of providing the reader with up-to-date answers and a broad understanding of the fundamental principles of hereditary ovarian cancer.