Association between blood lead and mercury levels and periodontitis in the Korean general population: analysis of the 2008-2009 Korean National Health and Nutrition Examination Survey data
Association between blood lead and mercury levels and periodontitis in the Korean general population: analysis of the 2008-2009 Korean National Health and Nutrition Examination Survey data
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DOI：
10.1007/s00420-012-0796-y
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发表时间：
2013-07-01
影响因子：
3
通讯作者：
Lee, Byung-Kook
中科院分区：
文献类型：
--
作者：
Kim, Yangho;Lee, Byung-Kook
我们提供了2008-2009年韩国国家健康和营养检查调查的数据，该调查是关于韩国成年人代表性样本中血铅和汞水平与牙周炎之间的关系。该分析仅限于20岁以下完成健康检查调查的参与者，包括血铅、镉和汞测量（n = 3 966）。将血铅、血汞、血镉作为自变量进行logistic回归分析，将血铅、血汞、血镉作为自变量，血铅、血汞加倍者患牙周炎的OR值和95%CI值分别为1.699（1.154-2.503）和1.394（1.057-1.838）。以血铅和汞的三分位数为自变量进行Logistic回归分析，经协变量调整后，最高三分位数的男性患牙周炎的OR和95%CI分别为1.756（1.184-2.604）和1.575（1.507-2.347）。在logistic回归分析中，使用对数转换的血镉或血镉的三分位数作为自变量，协变量调整后的OR在两种模型中均无统计学意义。与男性不同，在logistic回归分析中，女性使用相同的自变量，协变量调整后的OR值在任何血金属分析中均无统计学意义，血铅和汞水平与牙周炎之间的关联在韩国男性人群中无论变量类型（连续或分类）均显着。
We present data from the Korean National Health and Nutrition Examination Survey 2008-2009 regarding the association between blood lead and mercury levels and periodontitis in a representative sample of the adult South Korean population.The analysis was restricted to participants a parts per thousand yen20 years of age who completed the health examination survey, including blood lead, cadmium, and mercury measurements (n = 3,966). Odds ratios (ORs) for periodontitis were calculated for log-transformed blood metal levels and quartiles thereof after covariate adjustment.In a logistic regression analysis using log-transformed blood lead and mercury levels as independent variables after covariate adjustment, including blood lead, mercury, and cadmium, the ORs and 95 % CI values in men for having periodontitis with doubling of blood lead and mercury were 1.699 (1.154-2.503) and 1.394 (1.057-1.838), respectively. Furthermore, in a logistic regression analysis using tertiles of blood lead and mercury as independent variables after covariate adjustment, the ORs and 95 % CIs of men for having periodontitis in the highest tertile were 1.756 (1.184-2.604) and 1.575 (1.507-2.347), respectively. ORs in the logistic regression analysis for men using log-transformed blood cadmium or the tertile of blood cadmium as independent variables after covariate adjustments were not statistically significant in either model. Unlike men, ORs in the logistic regression analyses for women using the same independent variables after covariate adjustment were not statistically significant in any blood metal analysis.The association between blood lead and mercury levels and periodontitis was significant regardless of the type of variable (continuous or categorical) in the Korean male population.