Impact of Retinitis Pigmentosa on Quality of Life, Mental Health, and Employment Among Young Adults
Impact of Retinitis Pigmentosa on Quality of Life, Mental Health, and Employment Among Young Adults
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DOI：
10.1016/j.ajo.2017.02.016
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发表时间：
2017-05-01
影响因子：
4.2
通讯作者：
Mohand-Said, Saddek
中科院分区：
文献类型：
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作者：
Chaumet-Riffaud, Anne Elisabeth;Chaumet-Riffaud, Philippe;Mohand-Said, Saddek
目得：为了确定视功能和生活质量，教育，心理健康和就业之间的关系'与视网膜色素变性（RP）的年轻人。设计：横断面研究。方法：纳入148例（平均年龄38.2 +/- 7.1岁）诊断为RP，生活在法国。使用国家眼科研究所视觉功能问卷（VFQ-25）评估生活质量，使用医院焦虑和抑郁量表（BADS）评估精神状态，并使用专门设计的问卷评估就业情况。结果：22.3%的患者出现有限视力障碍，29.7%的患者出现低视力，48.0%的患者出现法律的失明。生活质量评分与残余视野之间存在相关性（P <0.0001）。心理健康评分提示焦虑36.5%，抑郁15.5%。残疾程度越高，发生率越低（P = 0.738，P = 0.134）。受过高等教育的受试者比例并没有随着残疾程度的增加而显著下降（P = 0.113）。就业率没有显着下降，残疾水平（P = 0.276）。报告抑郁症的受试者中该比例较低（P = 0.0414）。RP对就业的自评影响随着残疾程度的增加而增加（P = 0.02642）。结论：我们的结果与以前的结果不同，以前的结果显示RP的年轻人的教育率和就业率较低。进一步的研究是必要的，重点是心理健康，教育，工作场所的条件，就业援助对就业率与年龄和教育相匹配的正常视力的控制，以指导视力残疾的RP战略的影响。(C)2017爱思唯尔公司All rights reserved.
PURPOSE: To determine the relationship between visual function and quality of life, education, mental health, and employment' among young adults with retinitis pigmentosa (RP).DESIGN: Cross-sectional study.METHODS: Inclusion of 148 patients (mean age 38.2 +/- 7.1 years) diagnosed with RP, living in France. Quality of life was assessed using the National Eye Institute Visual Function Questionnaire (VFQ-25), mental state with the Hospital and Anxiety and Depression Scale (BADS), and employment with a specifically designed questionnaire.RESULTS: Limited visual impairment was noted in 22.3%, low vision in 29.7%, and legal blindness in 48.0%. There was a correlation between quality-of-life scores and residual visual field (P < .0001). Mental health scores were suggestive of anxiety in 36.5% and depression in 15.5%. The rates did not increase with disability level (P = .738, P = .134). The percentage of subjects with higher education did not significantly decrease with disability level (P = .113). The employment rate did not significantly decrease with, disability level (P = .276). It was lower in subjects reporting depression (P = .0414). Self-rated impact of RP on employment increased with disability level (P = .02642). "CONCLUSIONS: Our results differ from previous results showing lower education rates and employment rates in young adults with RP. Further research is warranted focusing on the impact of mental health, education, workplace conditions, and employment aids on employment rate vs age- and education-matched normally sighted controls to guide visual disability strategies in RP. (C) 2017 Elsevier Inc. All rights reserved.