Pinopodes as markers of endometrial receptivity in clinical practice

Pinopodes as markers of endometrial receptivity in clinical practice
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DOI:
10.1093/humrep/14.suppl_2.99
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发表时间:
1999-12-01
期刊:
影响因子:
6.1
通讯作者:
Nikas, G
Nikas, G
中科院分区:
医学1区
文献类型:
--
作者:
Nikas, G

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临床证据表明,人类存在一个狭窄的子宫容受性窗口,在黄体中期打开。同时,在子宫内膜上皮细胞的顶膜上形成胞饮突。为了在临床实践中开发一种用于感受性的特异性标记物,通过在自然、激素替代和刺激周期中连续进行子宫内膜活检来研究胞饮突形成的动力学。结果表明,
Clinical evidence indicates the existence in the human of a narrow window of uterine receptivity which opens during the mid-luteal phase. At the same time, formation of pinopodes on the apical membranes of the endometrial epithelial cells occurs. To develop a specific marker for receptivity in clinical practice, the kinetics of pinopode formation has been,investigated through sequential endometrial biopsying in natural, hormone replacement and stimulated cycles. The results show that pinopodes last