Gastric Xanthomas and Fundic Gland Polyps as Endoscopic Risk Indicators of Gastric Cancer

Gastric Xanthomas and Fundic Gland Polyps as Endoscopic Risk Indicators of Gastric Cancer
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DOI:
10.5009/gnl17136
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发表时间:
2019-07-01
期刊:
影响因子:
3.4
通讯作者:
Nakase, Hiroshi
Nakase, Hiroshi
中科院分区:
医学3区
文献类型:
--
作者:
Yamashita, Kentaro;Suzuki, Ryo;Nakase, Hiroshi

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背景/目标:胃底腺息肉(FGPs)、增生性息肉(HPs)和黄色瘤(XTs)是常见的胃良性病变,在大多数情况下,仅通过内镜检查即可诊断。本研究的目的是评估胃癌和这些良性病变之间的关系。方法:两名专家内镜审查了一系列胃镜图像。FGPs、HP和XTs通过内窥镜外观诊断,而所有胃癌均经病理证实。结果:在1,227例患者中,114例(9.3%)有胃癌的并发症或既往史。FGPs、HP和XTs的总患病率分别为9.4%、6.3%和14.2%。1.6%的患者同时存在HP和XTs,而其他组合则较为罕见。XTs在胃癌和非胃癌患者中的检出率分别为39.3%和11.5%(p
Background/Aims: Fundic gland polyps (FGPs), hyperplastic polyps (HPs), and xanthomas (XTs) are common benign gastric lesions that can be diagnosed by endoscopic appearance alone in most cases. The aim of this study was to evaluate associations between gastric cancer and these benign lesions. Methods: Two expert endoscopists reviewed a series of gastroscopy images. FGPs, HPs, and XTs were diagnosed by endoscopic appearance, whereas all gastric cancers were confirmed pathologically. Results: Of the 1,227 patients reviewed, 114 (9.3%) had a concurrent or past history of gastric cancer. The overall prevalences of FGPs, HPs and XTs were 9.4%, 6.3% and 14.2%, respectively. HPs and XTs coexisted in 1.6% of patients, whereas other combinations were rarer. XTs were observed in 39.3% and 11.5% of patients with and without gastric cancer, respectively (p