ALCOHOL-USE AND PERIODIC LIMB MOVEMENTS OF SLEEP
ALCOHOL-USE AND PERIODIC LIMB MOVEMENTS OF SLEEP
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DOI：
10.1111/j.1530-0277.1993.tb00747.x
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发表时间：
1993-02-01
影响因子：
3.2
通讯作者：
SHIPLEY, JE
中科院分区：
文献类型：
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作者：
ALDRICH, MS;SHIPLEY, JE
酒精会引起严重的睡眠障碍，但原因还不清楚。我们在一家睡眠障碍中心调查了大量患者饮酒与周期性肢体运动之间的关系。每天喝两杯或两杯以上酒精饮料的女性发生临床上显著的周期性腿部运动（每小时睡眠超过20次）的可能性是不喝酒精饮料的女性的3倍（25%对8%）。在男性中也发现了类似的关系（22%对13%）。此外，每天喝两杯或两杯以上的女性更有可能报告不宁腿的症状，并被诊断为不宁腿综合征。这些研究结果表明，周期性的腿部运动有助于睡眠障碍，在一个显着比例的酒精使用者。饮酒可能会增加易感个体周期性腿部运动的频率。另一方面，具有与周期性腿部运动相关的症状的受试者可能使用酒精来缓解症状，或者运动可能继发于酒精诱导的睡眠障碍。
Alcohol causes significant sleep disturbance but the causes are not well understood. We investigated the relationship between alcohol use and periodic limb movements in a large population of patients at a sleep disorders center. The likelihood of having a clinically significant number of periodic leg movements (more than 20 per hour of sleep) was increased 3-fold in women who consumed two or more alcoholic drinks per day compared with those who did not (25% versus 8%). A similar relation was found among men (22% versus 13%). In addition, women who consumed two or more drinks per day were more likely to report symptoms of restless legs and to be diagnosed with restless legs syndrome. These findings suggest that periodic leg movements contribute to sleep disturbance in a significant proportion of alcohol users. Alcohol use may increase the frequency of periodic leg movements in susceptible individuals. On the other hand, subjects with symptoms related to periodic leg movements may be using alcohol to relieve symptoms, or the movements may be secondary to alcohol-induced sleep disturbance.