Optical Coherence Tomography: Basic Concepts and Applications in Neuroscience Research.
Optical Coherence Tomography: Basic Concepts and Applications in Neuroscience Research.
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DOI：
10.1155/2017/3409327
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发表时间：
2017
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影响因子：
--
通讯作者：
Mokbul MI
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文献类型：
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作者：
Mokbul MI
光学相干层析成像是一种微米级的成像方式，它允许利用组织的后向散射特性对生物组织的微结构进行无标记的横截面成像。自20世纪90年代发明以来，OCT现在被广泛应用于神经科学的几个分支以及生物医学的其他领域。本文综述了OCT在神经科学的几个分支或分支中的应用，如神经成像、神经学、神经外科、神经病理学和神经胚胎学。本文简要总结了OCT在神经科学研究中的最新应用，包括比较，并讨论了仍然存在的挑战和机遇以及未来的发展方向。这项综述研究的主要目的是引起广大神经科学界的注意，以便最大限度地将OCT在神经科学的其他分支中应用，该研究也可能成为未来基于OCT的神经科学研究的基准。尽管有一些局限性，但事实证明，OCT在基础和临床神经科学研究中都是一个有用的成像工具。
Optical coherence tomography is a micrometer-scale imaging modality that permits label-free, cross-sectional imaging of biological tissue microstructure using tissue backscattering properties. After its invention in the 1990s, OCT is now being widely used in several branches of neuroscience as well as other fields of biomedical science. This review study reports an overview of OCT's applications in several branches or subbranches of neuroscience such as neuroimaging, neurology, neurosurgery, neuropathology, and neuroembryology. This study has briefly summarized the recent applications of OCT in neuroscience research, including a comparison, and provides a discussion of the remaining challenges and opportunities in addition to future directions. The chief aim of the review study is to draw the attention of a broad neuroscience community in order to maximize the applications of OCT in other branches of neuroscience too, and the study may also serve as a benchmark for future OCT-based neuroscience research. Despite some limitations, OCT proves to be a useful imaging tool in both basic and clinical neuroscience research.