Interim Analysis of Attrition Rates in Palliative Care Study on Dignity Therapy.
Interim Analysis of Attrition Rates in Palliative Care Study on Dignity Therapy.
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DOI:
10.1177/1049909121994309
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发表时间:
2021-12
期刊:
影响因子:
--
通讯作者:
Wilkie DJ
中科院分区:
文献类型:
--
作者:
Samuels V;Schoppee TM;Greenlee A;Gordon D;Jean S;Smith V;Reed T;Kittelson S;Quest T;O'Mahony S;Hauser J;Guay MOD;Rabow MW;Emanuel L;Fitchett G;Handzo G;Chochinov HM;Yao Y;Wilkie DJ
A routine threat to palliative care research is participants not completing studies. The purpose of this analysis was to quantify attrition rates mid-way through a palliative care study on Dignity Therapy and describe the reasons cited for attrition. Enrolled in the study were a total of 365 outpatients with cancer who were receiving outpatient specialty palliative care (mean age 66.7±7.3 years, 56% female, 72% White, 22% Black, 6% other race/ethnicity). These participants completed an initial screening for cognitive status, performance status, physical distress, and spiritual distress. There were 76 eligible participants who did not complete the study (58% female, mean age 67.9±7.3 years, 76% White, 17% Black, and 7% other race). Of those not completing the study, the average scores were 74.5±11.7 on the Palliative Performance Scale and 28.3±1.5 on the Mini-Mental Status Examination, whereas 22% had high spiritual distress scores and 45% had high physical distress scores. The most common reason for attrition was death/decline of health (47%), followed by patient withdrawal from the study (21%), and patient lost to follow-up (21%). The overall attrition rate was 24% and within the a priori projected attrition rate of 20%−30%. Considering the current historical context, this interim analysis is important because it will serve as baseline data on attrition prior to the outbreak of the COVID-19 pandemic. Future research will compare these results with attrition throughout the rest of the study, allowing analysis of the effect of the COVID-19 pandemic on the study attrition.
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