MR monitoring of tumour thermal therapy
MR monitoring of tumour thermal therapy
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DOI：
10.1007/bf02668650
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发表时间：
2001-08-01
影响因子：
2.3
通讯作者：
Saint-Jalmes, H
中科院分区：
文献类型：
--
作者：
Germain, D;Chevallier, P;Saint-Jalmes, H
肿瘤的热治疗包括通过热或冷输送的热疗和热消融，需要在线监测。由于其温度敏感性，磁共振成像（MRI）允许在治疗时进行热标测。基于水的质子共振频率（PRF），纵向弛豫时间T1，扩散系数和磁共振波谱成像（MRSI）的MR温度监测的不同技术进行了审查和辩论。尽管存在重要的缺点，但PRF方法在高磁场下使用最广泛且最有效。T1方法是可视化定性温度分布的最简单方法，并且在高达45-65 ℃的温度下，在肿瘤周围的组织中进行定量测量似乎是可能的。尽管其具有高的温度敏感性，但由于其高的运动敏感性，扩散方法在体内的应用受到限制。最近的MRSI技术似乎非常有前途的采集时间可以减少。文献结果表明，在1.5 T扫描仪中，对于16 mm（3）（1.5 x 1.5 x 7 mm）的体素，可以在13 s内实现约3 ℃的体内MR温度监测。(C)2001爱思唯尔科技有限公司。保留所有权利。
Thermal therapy of tumour including hyperthermia and thermal ablation by heat or cold delivery requires on line monitoring. Due to its temperature sensitivity, Magnetic Resonance Imaging (MRI) allows thermal mapping at the time of the treatment. The different techniques of MR temperature monitoring based on water proton resonance frequency (PRF), longitudinal relaxation time T1, diffusion coefficient and MR Spectroscopic Imaging (MRSI) are reviewed and debated. The PRF method appears the most widely used and the most efficient at high magnetic field in spite of important drawbacks. The T1 method is the easiest method of visualisation of qualitative temperature distribution and quantitative measurement seems possible in the tissue surrounding the tumour up to a temperature of 45-65 degreesC. Despite its high temperature sensitivity, application of the diffusion method in vivo is restricted due to its high motion sensitivity. The recent MRSI technique seems very promising provided acquisition times can be reduced. Results from the literature indicate that MR temperature monitoring in vivo can be achieved in vivo with a precision of about 3 degreesC in 13 s for a voxel of 16 mm(3) (1.5 x 1.5 x 7 mm) in 1.5 T scanners. (C) 2001 Elsevier Science B.V. All rights reserved.