In Vitro Assessment of Histology Verified Intracranial Atherosclerotic Disease by 1.5T Magnetic Resonance Imaging Concentric or Eccentric?
In Vitro Assessment of Histology Verified Intracranial Atherosclerotic Disease by 1.5T Magnetic Resonance Imaging Concentric or Eccentric?
复制标题
通过 1.5T 磁共振成像对组织学验证的颅内动脉粥样硬化疾病进行体外评估 同心还是偏心？
DOI：
10.1161/strokeaha.115.011086
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发表时间：
2016-02-01
期刊：
影响因子：
8.3
通讯作者：
Ng, Ho-Keung
中科院分区：
文献类型：
--
作者：
Yang, Wen-Jie;Chen, Xiang-Yan;Ng, Ho-Keung
Background and Purpose-Clinical trial studies show that plaque eccentricity (symmetry) is among the plaque features that have been associated with more frequent cerebrovascular events. Plaque eccentricity of intracranial atherosclerotic disease is unclear because of lacking of cerebral artery specimens.Methods-1.5T magnetic resonance imaging was performed in the postmortem brains to scan the cross sections of middle cerebral artery. Plaque eccentricity of histology-verified middle cerebral artery atherosclerosis was calculated on T1-weighted fat-suppressed sequence.Results-Validated by histology, concentric atherosclerotic plaques were identified in 46 middle cerebral arteries (63.9%) on magnetic resonance imaging and eccentric plaques in 26 arteries (26.1%). Eccentric plaques showed higher maximum wall thickness and lower minimum wall thickness than concentric plaques (both P
