Neurologic Manifestations of Systemic Disease ( A Wilkins

Neurologic Manifestations of Systemic Disease ( A Wilkins
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全身性疾病的神经系统表现(威尔金斯

DOI:
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发表时间:
2019
期刊:
影响因子:
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通讯作者:
S. Hickman
S. Hickman
中科院分区:
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文献类型:
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作者:
J. M. Jefferis;S. Hickman

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营养性视神经病变是严重视力丧失的潜在原因;然而,适当和及时的管理可以产生良好的视觉效果。这篇综述的目的是概述我们目前对营养性视神经病变的治疗和结果的理解。目前对营养性视神经病变的认识在很大程度上得益于对该疾病的一些广泛报道和调查,最著名的是20世纪90年代初古巴视神经病变的流行。最近,有一个新兴的文献围绕营养缺乏可能发生在病人谁接受了减肥手术。文献中也继续有一系列的病例报告,增加了我们的理解。营养性视神经病变与中毒性视神经病变和遗传性视神经病变有很大的重叠,不应与这些情况分开考虑。营养性视神经病变的主要治疗包括识别和替换缺乏的营养物质以及识别和消除致病毒素。同样重要的是,确定起作用的遗传因素,并考虑可能起作用的更广泛的社会、经济和社会因素。
Purpose of review Nutritional optic neuropathy is a potential cause of severe visual loss; however, appropriate and timely management can result in excellent visual outcomes. The purpose of this review is to outline our current understanding of the treatment and outcomes for nutritional optic neuropathy. Recent findings Current understanding of nutritional optic neuropathy has been greatly aided by some well-reported and investigated epidemics of the condition, most notably the Cuban epidemic optic neuropathy of the early 1990s. More recently, there is an emerging literature surrounding nutritional deficiencies that can occur in patients who have undergone bariatric surgery. There also continues to be a stream of case reports in the literature that add to our understanding. Nutritional optic neuropathy has a great deal of overlap with toxic optic neuropathies and hereditary optic neuropathies and should not be thought of in isolation from these conditions. Summary The mainstay of treatment for nutritional optic neuropathy involves identifying and replacing deficient nutrients as well as identifying and eliminating contributory toxins. It is also important to identify contributory genetic factors and to consider the broader social, economic and societal factors which may contribute.
莱伯遗传性视神经病:坏习惯,视力不好?
DOI: 10.1093/brain/awp195
发表时间: 2009
期刊: Brain : a journal of neurology
影响因子: --
作者:
Newman,NancyJ
通讯作者: Newman,NancyJ
获得性线粒体损伤是视神经疾病的一个原因。
DOI: --
发表时间: 1998
期刊: Transactions of the American Ophthalmological Society
影响因子: --
作者:
Sadun,A
通讯作者: Sadun,A