Investigations of step-growth thiol-ene polymerizations for novel dental restoratives
Investigations of step-growth thiol-ene polymerizations for novel dental restoratives
复制标题
DOI：
10.1016/j.dental.2005.04.001
复制
发表时间：
2005-12-01
期刊：
影响因子：
5
通讯作者：
Bowman, CN
中科院分区：
文献类型：
--
作者：
Lu, H;Carioscia, JA;Bowman, CN
目的：本工作的目的是探索利用逐步生长的硫醇-烯光聚合制备新型牙科修复材料的可行性。特别是，我们的目标是显著降低聚合收缩和收缩应力白色，与目前基于二甲基丙烯酸酯的体系相比，保持足够的物理性能。方法：硫醇-烯体系由三烯丙基-1，3，5-三嗪-2，4，6-三酮(TATO)和季戊四醇四硫基丙酸酯(PETMP)的4：3摩尔混合物组成。同时测定了收缩应力和官能团转化率。对未反应单体进行了溶剂萃取，并对形成的聚合物网络进行了动态力学分析。结果：PETMP/TATATO的光聚合速率比相同条件下固化的Bis-GMA/TEGDMA的最大聚合速率快6倍。收缩应力和转化率的同时测量结果表明，收缩应力的开始与延迟的GET点转化率一致，对于化学计量比为3：4的PETMP/TATATO树脂配方，预测的转化率为41%。PETMP/TATATO体系的最大收缩应力约为0.4 Mpa，仅为Bis-GMA/TEGDMA体系最大收缩应力的14%左右。无论是合适的还是不合适的PETMP/TATO体系，都获得了足够的弯曲强度和弯曲模量值。重要的是：显著降低了收缩应力，提高了聚合速率，显著提高了官能团转化率，减少了可浸出物种，这些都有利于硫醇-烯体系作为潜在的牙科修复材料的使用。(C)2005年牙科材料学会。爱思唯尔有限公司出版。保留所有权利。
Objectives: The goat of this work was to investigate the feasibility of formulating novel dental restorative materials that utilize a step-growth thiol-ene photopolymerization. Particularly, we are aiming to significantly reduce the polymerization shrinkage and shrinkage stress white retaining adequate physical properties as compared to current dimethacrylatre-based systems.Methods: The thiol-ene system is composed of a 4:3 molar mixture of triallyl-1,3,5-triazine-2,4,6-trione (TATATO) and pentaerythritol tetramercaptopropionate (PETMP). The simultaneous measurement of shrinkage stress and functional group conversion was performed. Solvent extraction of unreacted monomers and dynamic mechanical analysis on the polymer networks that were formed were also studied. Flexural strength was measured for both fitted and unfitted PETMP/TATATO and Bis-GMA/TEGDMA systems.Results: Photopolymerization of PETMP/TATATO occurs at a much higher rate, with the maximum polymerization rate six times faster, than Bis-GMA/TEGDMA cured under the identical conditions. The results from the simultaneous measurement of shrinkage stress and conversion showed that the onset of shrinkage stress coincides with the delayed get point conversion, which is predicted to be 41% for the 3:4 stoichiometric PETMP/TATATO resin composition. The maximum shrinkage stress developed for PETMP/TATATO was about 0.4 MPa, which was only approximately 14% of the maximum shrinkage stress of the Bis-GMA/TEGDMA system. Adequate flexural strength and flexural modulus values were obtained for both fitted and unfitted PETMP/TATATO systems.Significance: The dramatically reduced shrinkage stress, increased polymerization rate, significance increased functional group conversion, and decreased leachable species are all benefits for the use-of thiol-ene systems as potential dental restorative materials. (C) 2005 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.