TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system.

TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system.
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Foregut(Neuro)内分泌肿瘤的TNM分期:包括分级系统在内的共识提案。

DOI:
10.1007/s00428-006-0250-1
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发表时间:
2006-10
期刊:
影响因子:
3.5
通讯作者:
Wiedenmann, B.
Wiedenmann, B.
中科院分区:
医学3区
文献类型:
--
作者:
Rindi, G.;Kloeppel, G.;Alhman, H.;Caplin, M.;Couvelard, A.;de Herder, W. W.;Erikssson, B.;Falchetti, A.;Falconi, M.;Komminoth, P.;Koerner, M.;Lopes, J. M.;McNicol, A-M.;Nilsson, O.;Perren, A.;Scarpa, A.;Scoazec, J. -Y;Wiedenmann, B.

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消化系统内分泌肿瘤患者的管理需要标准,促使欧洲神经内分泌肿瘤协会(ENETS)组织了第一次共识会议,会议在(罗马)弗拉斯卡蒂举行,以欧洲神经内分泌肿瘤协会(ENETS)最近发布的关于消化系统神经内分泌肿瘤诊断和治疗的指南为基础。在这里,我们报告了胃、十二指肠和胰腺的前肠网络的肿瘤转移方案,该方案是在这次会议上设计、讨论并一致通过的。此外,我们报告了基于有丝分裂计数和Ki-67指数的消化网分级的工作公式的建议。这项建议需要验证,旨在帮助临床医生对患者进行分层、治疗和随访。
The need for standards in the management of patients with endocrine tumors of the digestive system prompted the European Neuroendocrine Tumor Society (ENETS) to organize a first Consensus Conference, which was held in Frascati (Rome) and was based on the recently published ENETS guidelines on the diagnosis and treatment of digestive neuroendocrine tumors (NET). Here, we report the tumor–node–metastasis proposal for foregut NETs of the stomach, duodenum, and pancreas that was designed, discussed, and consensually approved at this conference. In addition, we report the proposal for a working formulation for the grading of digestive NETs based on mitotic count and Ki-67 index. This proposal, which needs to be validated, is meant to help clinicians in the stratification, treatment, and follow-up of patients.
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