Severe burn injury in Europe: a systematic review of the incidence, etiology, morbidity, and mortality.

Severe burn injury in Europe: a systematic review of the incidence, etiology, morbidity, and mortality.
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DOI:
10.1186/cc9300
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发表时间:
2010
期刊:
Critical care (London, England)
影响因子:
--
通讯作者:
Blot S
Blot S
中科院分区:
其他
文献类型:
--
作者:
Brusselaers N;Monstrey S;Vogelaers D;Hoste E;Blot S

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烧伤是一种严重的病理学,可能导致严重的发病率和死亡率,但它也有相当大的健康经济影响。本研究的目的是描述欧洲严重烧伤住院人群,包括发病率、病因、危险因素、死亡率和死亡原因。系统性文献检索(1985年至2009年)涉及PubMed、Web of Science和搜索引擎Google。参考文献列表和科学引文索引用于手动搜索(滚雪球)。仅纳入了以流行病学问题(例如,发病率和结局)为主要主题的欧洲严重烧伤住院人群(二级和三级护理)研究。对英语、法语和荷兰语设置了语言限制。检索得到76项符合条件的研究,总共包括超过186,500例患者。严重烧伤的年发病率为0.2至2.9/10 000居民,并呈逐年下降趋势。近50%的患者年龄小于16岁,约60%为男性患者。火焰、烫伤和接触性烧伤是总人口中最常见的原因,但在儿童中,烫伤明显占主导地位。死亡率通常在1.4%至18%之间,并随着时间的推移而下降。死亡的主要危险因素是年龄较大和烧伤面积总百分比较高以及慢性疾病。(多)器官衰竭和败血症是最常报告的死亡原因。早期死亡(<48小时)的主要原因是烧伤休克和吸入性损伤。尽管缺乏一个大规模的欧洲烧伤登记,更多的流行病学信息是关于严重烧伤住院人群比一般假设。然而,国家和国际登记系统仍然是必要的,以便更好地针对预防运动,并进一步提高全面烧伤护理的成本效益。
Burn injury is a serious pathology, potentially leading to severe morbidity and significant mortality, but it also has a considerable health-economic impact. The aim of this study was to describe the European hospitalized population with severe burn injury, including the incidence, etiology, risk factors, mortality, and causes of death. The systematic literature search (1985 to 2009) involved PubMed, the Web of Science, and the search engine Google. The reference lists and the Science Citation Index were used for hand searching (snowballing). Only studies dealing with epidemiologic issues (for example, incidence and outcome) as their major topic, on hospitalized populations with severe burn injury (in secondary and tertiary care) in Europe were included. Language restrictions were set on English, French, and Dutch. The search led to 76 eligible studies, including more than 186,500 patients in total. The annual incidence of severe burns was 0.2 to 2.9/10,000 inhabitants with a decreasing trend in time. Almost 50% of patients were younger than 16 years, and ~60% were male patients. Flames, scalds, and contact burns were the most prevalent causes in the total population, but in children, scalds clearly dominated. Mortality was usually between 1.4% and 18% and is decreasing in time. Major risk factors for death were older age and a higher total percentage of burned surface area, as well as chronic diseases. (Multi) organ failure and sepsis were the most frequently reported causes of death. The main causes of early death (<48 hours) were burn shock and inhalation injury. Despite the lack of a large-scale European registration of burn injury, more epidemiologic information is available about the hospitalized population with severe burn injury than is generally presumed. National and international registration systems nevertheless remain necessary to allow better targeting of prevention campaigns and further improvement of cost-effectiveness in total burn care.
DOI: 10.1007/s00134-005-2819-6
发表时间: 2005-12-01
影响因子: 38.9
作者:
Brusselaers, N;Hoste, EAJ;Blot, SI
通讯作者: Blot, SI
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影响因子: 2.7
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DOI: 10.1016/j.burns.2008.02.010
发表时间: 2008-12-01
期刊: BURNS
影响因子: 2.7
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DOI: 10.1016/s0305-4179(01)00095-x
发表时间: 2002-05-01
期刊: BURNS
影响因子: 2.7
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DOI: 10.1002/bjs.6329
发表时间: 2009-01-01
影响因子: 9.6
作者:
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通讯作者: Hoste, E.